Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15048635 | 0.78 | CES1 (0.50) | ALDH1A1KMT2AMAPTPARP10NPC1 | |
| SCHEMBL27540267 | 0.78 | ALDH1A1 (0.42) | ALDH1A1KMT2AMAPTPARP10NPC1 | |
| SCHEMBL27529609 | 0.77 | ALDH1A1 (0.44) | ALDH1A1KMT2AMAPTPARP10NPC1 | |
| SCHEMBL7609100 | 0.73 | MEN1 (0.47) | ALDH1A1KMT2ANPC1RAB9A | |
| SCHEMBL10866803 | 0.73 | PPARG (0.51) | ALDH1A1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL7609105 | 0.73 | MEN1 (0.47) | ALDH1A1KMT2ANPC1RAB9A | |
| SCHEMBL11475913 | 0.73 | ALDH1A1 (0.52) | ALDH1A1KMT2ASMN1; SMN2MAPK1L3MBTL1 | |
| SCHEMBL883026 | 0.73 | SLC16A3 (0.55) | ALDH1A1KMT2AMAPK1L3MBTL1SLC6A2 | |
| SCHEMBL8717382 | 0.72 | KMT2A (0.44) | ALDH1A1KMT2AMAPTPARP10NPC1 | |
| SCHEMBL10349973 | 0.72 | MEN1 (0.49) | ALDH1A1KMT2ASMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009117278-A2 | PROCESSES FOR PREPARING (AMINO-PYRAZOLOPYRIDINYL)METHOXY SUBSTITUTED BIARYL ETHERS | MERCK & CO., INC. (US) | 2009-09-24 | — | — | WO | disclosed |