Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3E | A5X5Y0 | 3/20 | 1.00 |
| ▸ | HTR3B | O95264 | 3/20 | 1.00 |
| ▸ | HTR3A | P46098 | 3/20 | 1.00 |
| ▸ | HTR3D | Q70Z44 | 3/20 | 1.00 |
| ▸ | HTR3C | Q8WXA8 | 3/20 | 1.00 |
| ▸ | MEN1 | O00255 | 2/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 2/20 | 1.00 |
| ▸ | CYP1A2 | P05177 | 1/20 | 1.00 |
| ▸ | CYP2D6 | P10635 | 1/20 | 1.00 |
| ▸ | ALOX15 | P16050 | 1/20 | 1.00 |
| ▸ | TSHR | P16473 | 1/20 | 1.00 |
| ▸ | NFKB1 | P19838 | 1/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.53 |
| ▸ | PTPN11 | Q06124 | 3/20 | 0.48 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.48 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.47 |
| ▸ | PAK4 | O96013 | 1/20 | 0.47 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3282207 | 0.98 | HTR3E (0.97) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| Hydrochloric Acid SCHEMBL29816588 | 0.98 | HTR3E (0.97) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL7389337 | 0.90 | HTR3E (0.82) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| Hydrochloric Acid SCHEMBL9005394 | 0.89 | HTR3E (0.79) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL3536632 | 0.83 | KMT2A (0.71) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL7382691 | 0.82 | HTR3E (0.70) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL1810974 | 0.80 | HTR3E (0.70) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL16334097 | 0.80 | HTR3E (0.70) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL7282795 | 0.79 | HTR3E (0.66) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL21991791 | 0.79 | HTR3E (0.66) | HTR3EHTR3BHTR3AHTR3DHTR3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 90 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025096366-A1 | CONJUGATES FOR DELIVERY ACROSS THE BLOOD BRAIN BARRIER | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) | 2025-05-08 | — | — | WO | claimed |
| US-20220347166-A1 | Schizophrenic Disorder Treatment using Combination Therapy | CAMBRIDGE COGNITION LIMITED (GB) | 2022-11-03 | — | — | US | claimed |
| CN-114845717-A | Treatment of schizophrenia disorders using combination therapy | 剑桥认知有限公司 | 2022-08-02 | — | — | CN | claimed |
| US-20220146492-A1 | CELL MEMBRANE PERMEABILITY RESTORING THERAPY | SHINE IAN BASIL (US) | 2022-05-12 | — | — | US | claimed |
| EP-3953000-A1 | CELL MEMBRANE PERMEABILITY RESTORING THERAPY | Shine, Ian Basil (US) | 2022-02-16 | — | — | EP | claimed |
| WO-2021078810-A1 | SCHIZOPHRENIC DISORDER TREATMENT USING COMBINATION THERAPY | CAMBRIDGE COGNITION LTD. (GB) | 2021-04-29 | — | — | WO | claimed |
| EP-3185946-B1 | MULTI-ELECTRODE ARRAY FOR SPINAL CORD EPIDURAL STIMULATION | UNIV CALIFORNIA (US) | 2019-10-09 | — | — | EP | claimed |
| EP-1235565-B1 | USE OF 5HT 3 AGONISTS FOR RELAXING THE FUNDUS | JANSSEN PHARMACEUTICA NV (BE) | 2005-12-28 | — | — | EP | claimed |
| US-20050209270-A1 | Use of 5HT3 agonists for relaxing the fundus | MEULEMANS ANN LOUISE G | 2005-09-22 | — | — | US | claimed |
| US-20050119297-A1 | Use of 5HT3 agonists for relaxing the fundus | MEULEMANS ANN L G (BE) | 2005-06-02 | — | — | US | claimed |
| US-6284277-B1 | NONPROTEIN | SANOFI-SYNTHELABO (FR) | 2001-09-04 | — | — | US | claimed |
| WO-2001037824-A1 | USE OF 5HT3 AGONISTS FOR RELAXING THE FUNDUS | JANSSEN PHARMACEUTICA N.V. (BE) | 2001-05-31 | — | — | WO | claimed |
| EP-0506545-B1 | Use of 4-amino-1-(2-pyridyl)piperidines as 5-HT3-agonists for the treatment and prophylaxis of serotoninergic dysfunctions | SANOFI SA (FR) | 1998-12-30 | — | — | EP | claimed |
| CN-1203527-A | Stable freeze-dried pharmaceutical formulation | SANOFI SA (FR) | 1998-12-30 | — | — | CN | claimed |
| US-5604245-A | Use of 4-amino-1-(2-pyridyl)piperidines for the preparation of a medicament for the treatment of conditions deriving from disorders of the serotoninergic systems mediated by 5-HT3 receptors | ELF SANOFI (FR) | 1997-02-18 | — | — | US | claimed |
| EP-0535626-A1 | Use of 4-amino-1-(2-pyridyl)piperidines as anti-convulsivant and anti-epileptic agents | SANOFI (FR) | 1993-04-07 | — | — | EP | claimed |
| EP-0506545-A2 | Use of 4-amino-1-(2-pyridyl)piperidines as 5-HT3-agonists for the treatment and prophylaxis of serotoninergic dysfunctions | SANOFI (FR) | 1992-09-30 | — | — | EP | claimed |
| US-4409228-A | ANOREXIGENIC AGENTS | SANOFI (FR) | 1983-10-11 | — | — | US | claimed |
| EP-0021973-B1 | ANORECTIC AMINO PIPERIDINES, PROCESS FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM | SANOFI S.A. (FR) | 1982-12-08 | — | — | EP | claimed |
| EP-0021973-A2 | Anorectic amino piperidines, process for their preparation and medicaments containing them | SANOFI S.A. (FR) | 1981-01-07 | — | — | EP | claimed |