Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.45 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 2/20 | 0.40 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | HRH2 | P25021 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4229151 | 0.80 | SCN1A (0.47) | HRH3ALDH1A1SMN1; SMN2CYP1A2CYP2D6 | |
| SCHEMBL10425923 | 0.78 | CHRNB4 (0.54) | HRH3LTA4HKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL7392194 | 0.78 | MAOB (0.44) | HRH3LTA4HCYP1A2CYP2D6KMT2A | |
| Hydrochloric Acid SCHEMBL10426292 | 0.77 | CHRNB4 (0.53) | HRH3LTA4HKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL7367095 | 0.77 | NR5A1 (0.43) | LTA4HSIGMAR1 | |
| SCHEMBL4687709 | 0.77 | MAOA (0.52) | HRH3LTA4HPTGS1PTGS2KDM4E | |
| SCHEMBL7403861 | 0.77 | KMT2A (0.44) | HRH3LTA4HALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL7403380 | 0.77 | MAOB (0.43) | HRH3LTA4HCYP1A2CYP2D6KCNH2 | |
| SCHEMBL7398553 | 0.76 | KCNH2 (0.43) | LTA4HCYP2D6KCNH2 | |
| Hydrochloric Acid SCHEMBL7397296 | 0.76 | KMT2A (0.43) | HRH3LTA4HALDH1A1CYP2D6KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090233910-A1 | Npy antagonists, preparation and uses | CEREP (FR) | 2009-09-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090233910-A1 | Npy antagonists, preparation and uses | NPY1R, NPY5R, NPY2R | HRH3 210/4885LTA4H 1731/4885PTGS1 1889/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.