⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL771914 | 0.91 | MEN1 (0.56) | — | |
| SCHEMBL1196794 | 0.78 | — | — | |
| SCHEMBL2899860 | 0.77 | MEN1 (0.80) | — | |
| SCHEMBL786679 | 0.77 | SMN1; SMN2 (0.59) | — | |
| SCHEMBL27840293 | 0.74 | CA12 (0.56) | — | |
| SCHEMBL11741744 | 0.74 | MEN1 (0.85) | — | |
| Hydrochloric Acid SCHEMBL28000052 | 0.74 | MEN1 (0.76) | — | |
| SCHEMBL55421 | 0.74 | — | — | |
| SCHEMBL55420 | 0.74 | — | — | |
| Hydrochloric Acid SCHEMBL27660773 | 0.74 | MEN1 (0.76) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1233 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4397366-A2 | GLYCYRRHETINIC ACID DERIVATIVES FOR TREATING HYPERKALEMIA | Ardelyx, Inc. (US) | 2024-07-10 | — | — | EP | claimed |
| EP-3792251-B1 | NOVEL SULFONYLAMINOBENZAMIDE COMPOUNDS AS ANTHELMINTICS | ELANCO TIERGESUNDHEIT AG (CH) | 2024-02-14 | — | — | EP | claimed |
| EP-3572400-B1 | EZH2 INHIBITOR AND USE THEREOF | TARAPEUTICS SCIENCE INC (CN) | 2023-10-04 | — | — | EP | claimed |
| US-11768319-B2 | Glycyrrhetinic acid derivatives for treating hyperkalemia | ARDELYX, INC. (US) | 2023-09-26 | — | — | US | claimed |
| US-20230273354-A1 | GLYCYRRHETINIC ACID DERIVATIVES FOR TREATING HYPERKALEMIA | ARDELYX, INC. (US) | 2023-08-31 | — | — | US | claimed |
| EP-3947369-A1 | HETEROCYCLIC COMPOUNDS AS BCR-ABL INHIBITORS | Ascentage Pharma (Suzhou) Co., Ltd. (CN) | 2022-02-09 | — | — | EP | claimed |
| EP-3137468-B1 | COMPOUNDS AND COMPOSITIONS AS TOLL-LIKE RECEPTOR 7 AGONISTS | NOVARTIS AG (CH) | 2021-10-06 | — | — | EP | claimed |
| CN-112920199-A | Piperazinone substituent or derivative thereof, and preparation method, application and pharmaceutical composition thereof | 四川大学 | 2021-06-08 | — | — | CN | claimed |
| US-20210163524-A1 | GLYCYRRHETINIC ACID DERIVATIVES FOR TREATING HYPERKALEMIA | ARDELYX, INC. (US) | 2021-06-03 | — | — | US | claimed |
| EP-3186227-B1 | NOVEL SULFONYLAMINOBENZAMIDE COMPOUNDS AS ANTHELMINTICS | ELANCO TIERGESUNDHEIT AG (CH) | 2021-03-24 | — | — | EP | claimed |
| US-5001137-A | Pyridine compounds and pharmaceutical use thereof | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1991-03-19 | — | — | US | claimed |
| EP-0368175-A1 | 3S,7S-3-(Morpholinocarbonyl)-5-(2-chlorphenyl)-7,10-dimethyl-3,4-dihydro-2H,7H-cyclopenta[4,5]thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine. | BOEHRINGER INGELHEIM KG (DE) | 1990-05-16 | — | — | EP | claimed |
| US-4845079-A | HYPOTENSIVE, RENIN INHIBITION | ABBOTT LABORATORIES | 1989-07-04 | — | — | US | claimed |
| EP-0308885-A1 | Derivatives of d-glutamic acid and d-aspartic acid | ABBOTT LABORATORIES (US) | 1989-03-29 | — | — | EP | claimed |
| WO-1989002431-A1 | DERIVATIVES OF D-GLUTAMIC ACID AND D-ASPARTIC ACID | ABBOTT LABORATORIES (US) | 1989-03-23 | — | — | WO | claimed |
| EP-0303934-A1 | 2-Cyano-2-oximino-acetamides | BAYER AG (DE) | 1989-02-22 | — | — | EP | claimed |
| EP-0264773-A1 | 4,5-dihydro and 4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidines | AMERICAN CYANAMID COMPANY (US) | 1988-04-27 | — | — | EP | claimed |
| EP-0229667-A2 | Peptidylaminodiols | ABBOTT LABORATORIES (US) | 1987-07-22 | — | — | EP | claimed |
| US-4610983-A | N-acyl acidic amino acid diamide derivative, a salt thereof, and an anti-ulcer agent containing the same | TOYAMA CHEMICAL CO., LTD. (JP) | 1986-09-09 | — | — | US | claimed |
| EP-0139627-A1 | Process for the preparation of 5,10-dihydro-1H-dibenzo [B,E] [1,4] diazepin-11-ones substituted in position 5 | ARZNEIMITTELWERK DRESDEN GmbH (DE) | 1985-05-02 | — | — | EP | claimed |