⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL786679 | 0.79 | SMN1; SMN2 (0.59) | — | |
| SCHEMBL2899860 | 0.79 | MEN1 (0.80) | — | |
| SCHEMBL6040035 | 0.78 | MEN1 (0.62) | — | |
| SCHEMBL3954355 | 0.78 | MEN1 (0.86) | — | |
| SCHEMBL9541712 | 0.77 | — | — | |
| SCHEMBL11741744 | 0.77 | MEN1 (0.85) | — | |
| Hydrochloric Acid SCHEMBL27660773 | 0.77 | MEN1 (0.76) | — | |
| SCHEMBL27840293 | 0.77 | CA12 (0.56) | — | |
| Hydrochloric Acid SCHEMBL28000052 | 0.77 | MEN1 (0.76) | — | |
| SCHEMBL55421 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2316 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117986215-A | 2-Phenyl-4-acyl benzofurans, preparation and application thereof | 中国医学科学院药物研究所 | 2024-05-07 | — | — | CN | claimed |
| US-10919856-B2 | Cyclohexene compounds and use thereof | GUANGZHOU HENOVCOM BIOSCIENCE CO. LTD. (CN) | 2021-02-16 | — | — | US | claimed |
| EP-2786990-B1 | 2-AMINATED METHYLENE OR 2-ESTERIFIED METHYLENE TANSHINONE DERIVATIVES, AND PREPARATION METHOD AND APPLICATION THEREOF | HANGZHOU BENSHENG PHARMACEUTICAL CO LTD (CN) | 2018-08-08 | — | — | EP | claimed |
| EP-2350068-B1 | UREA DERIVATIVES OF SUBSTITUTED NORTROPANES, MEDICAMENTS CONTAINING SUCH COMPOUNDS AND THEIR USE | BOEHRINGER INGELHEIM INT (DE) | 2017-08-30 | — | — | EP | claimed |
| US-9328083-B2 | 2-aminated methylene or 2-esterified methylene tanshinone derivatives, and preparation method and application thereof | HANGZHOU BENSHENG PHARMACEUTICAL CO., LTD. (CN) | 2016-05-03 | — | — | US | claimed |
| EP-2318403-B1 | Aryl- and heteroarylcarbonyl derivatives of substituted nortropanes, medicaments containing such compounds and their use | BOEHRINGER INGELHEIM INT (DE) | 2015-12-23 | — | — | EP | claimed |
| EP-2885279-A1 | CYCLOPENTYLPYRAZOLES AS N-TYPE CALCIUM CHANNEL BLOCKERS | Janssen Pharmaceutica, N.V. (BE) | 2015-06-24 | — | — | EP | claimed |
| US-20150126552-A1 | 2-AMINATED METHYLENE OR 2-ESTERIFIED METHYLENE TANSHINONE DERIVATIVES, AND PREPARATION METHOD AND APPLICATION THEREOF | HANGZHOU BENSHENG PHARMACEUTICAL CO., LTD. (CN) | 2015-05-07 | — | — | US | claimed |
| US-8946438-B2 | Benzamides, production thereof, and use thereof as medicaments | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2015-02-03 | — | — | US | claimed |
| EP-2786990-A1 | 2-AMINATED METHYLENE OR 2-ESTERIFIED METHYLENE TANSHINONE DERIVATIVES, AND PREPARATION METHOD AND APPLICATION THEREOF | Hangzhou Bensheng Pharmaceutical Co., Ltd. (CN) | 2014-10-08 | — | — | EP | claimed |
| US-5753652-A | Antiretroviral hydrazine derivatives | NOVARTIS CORPORATION (US) | 1998-05-19 | — | — | US | claimed |
| EP-0604368-B1 | Anti retroviral hydrazine derivatives | CIBA GEIGY AG (CH) | 1996-09-18 | — | — | EP | claimed |
| EP-0719552-A2 | Pharmaceutical composition comprising a quinone derivative or a hydroquinone thereof for treating dermatitis | Takeda Chemical Industries, Ltd. (JP) | 1996-07-03 | — | — | EP | claimed |
| EP-0653427-A1 | Galanthamine derivatives, a process for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1995-05-17 | — | — | EP | claimed |
| US-5405847-A | Antiallergic, antiasthmatic, anxiolytic, hypotensive agents | ASTA MEDICA AKTIENGESELLSCHAFT (DE) | 1995-04-11 | — | — | US | claimed |
| EP-0229667-B1 | Peptidylaminodiols | ABBOTT LAB (US) | 1994-07-13 | — | — | EP | claimed |
| EP-0604368-A1 | Anti retroviral hydrazine derivatives | CIBA-GEIGY AG (CH) | 1994-06-29 | — | — | EP | claimed |
| EP-0584487-A2 | 4,5-Dihydro-4-oxopyrrolo (1,2-a) quinoxalines and aza-analoges and process for their preparation | ASTA Medica Aktiengesellschaft (DE) | 1994-03-02 | — | — | EP | claimed |
| US-4845079-A | HYPOTENSIVE, RENIN INHIBITION | ABBOTT LABORATORIES | 1989-07-04 | — | — | US | claimed |
| EP-0229667-A2 | Peptidylaminodiols | ABBOTT LABORATORIES (US) | 1987-07-22 | — | — | EP | claimed |