Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 13/20 | 0.67 |
| ▸ | PNP | P00491 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 5/20 | 0.40 |
| ▸ | ATP1A1 | P05023 | 1/20 | 0.39 |
| ▸ | ATP1B1 | P05026 | 1/20 | 0.39 |
| ▸ | ATP1A3 | P13637 | 1/20 | 0.39 |
| ▸ | ATP1B2 | P14415 | 1/20 | 0.39 |
| ▸ | ATP1A2 | P50993 | 1/20 | 0.39 |
| ▸ | ATP1B3 | P54709 | 1/20 | 0.39 |
| ▸ | FXYD2 | P54710 | 1/20 | 0.39 |
| ▸ | ATP1A4 | Q13733 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 2/20 | 0.37 |
| ▸ | NOS3 | P29474 | 1/20 | 0.34 |
| ▸ | NOS2 | P35228 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1691104 | 0.98 | TYMP (0.68) | TYMPPNPIDO1ATP1A1ATP1B1 | |
| Hydrochloric Acid SCHEMBL1682955 | 0.79 | TYMP (1.00) | TYMPIDO1 | |
| Hydrochloric Acid SCHEMBL1682948 | 0.75 | TYMP (0.62) | TYMPIDO1NOS1NOS3NOS2 | |
| SCHEMBL6572727 | 0.70 | TYMP (0.52) | TYMPPNP | |
| Hydrochloric Acid SCHEMBL1690736 | 0.70 | TYMP (0.41) | TYMPPNP | |
| SCHEMBL6574092 | 0.66 | TYMP (0.50) | TYMPPNP | |
| SCHEMBL11002379 | 0.66 | TYMP (0.50) | TYMPPNP | |
| Hydrochloric Acid SCHEMBL1690734 | 0.64 | TYMP (0.51) | TYMPPNP | |
| SCHEMBL10655644 | 0.63 | TYMP (0.47) | TYMPPNP | |
| Hydrochloric Acid SCHEMBL11694179 | 0.62 | ATP1A1 (0.63) | IDO1ATP1A1ATP1B1ATP1A3ATP1B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2036903-B1 | POTENTIATOR OF RADIATION THERAPY | TAIHO PHARMACEUTICAL CO LTD (JP) | 2012-05-23 | — | — | EP | disclosed |
| EP-2036903-A1 | POTENTIATOR OF RADIATION THERAPY | Taiho Pharmaceutical Co., Ltd. (JP) | 2009-03-18 | — | — | EP | disclosed |