SCHEMBL423522

SCHEMBL423522

COCn1cc[n+](C)c1F

nearest known ligand 0.36

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ACHE P22303 2/20 0.36
LMNA P02545 1/20 0.31
HPGD P15428 1/20 0.31
HTT P42858 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
HDAC8 Q9BY41 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL424276 0.81 HDAC8 (0.36) ACHEHDAC8
SCHEMBL422423 0.78 ACHE (0.56) ACHEHDAC8
SCHEMBL424958 0.77
SCHEMBL2869037 0.73 ACHE (0.34) ACHE
SCHEMBL424227 0.72 ACHE (0.36) ACHELMNAHPGDHTTSMN1; SMN2
SCHEMBL427605 0.71 KMT2A (0.39) LMNAHPGDHTTSMN1; SMN2HDAC8
SCHEMBL5944565 0.64 HDAC8 (0.39) ACHEHTTSMN1; SMN2HDAC8
SCHEMBL3457315 0.64 SMN1; SMN2 (0.35) ACHELMNAHPGDHTTSMN1; SMN2
SCHEMBL17706417 0.63 ACHE (0.65) ACHE
SCHEMBL3458267 0.63 CA1 (0.38) ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1981034-B1 ACTUATOR ELEMENT DAIKIN IND LTD (JP) 2016-01-13 EP disclosed
US-8637601-B2 Fluorine-containing polymer having heteroaromatic ring DAIKIN INDUSTRIES, LTD. (JP) 2014-01-28 US disclosed
US-8545732-B2 Electrode film for polymer actuator element, and polymer actuator element comprising the same DAIKIN INDUSTRIES, LTD. (JP) 2013-10-01 US disclosed
EP-1983008-B1 FLUORINE-CONTAINING POLYMER CONTAINING HETEROAROMATIC RING DAIKIN IND LTD (JP) 2012-12-26 EP disclosed
US-20120271005-A1 FLUORINE-CONTAINING POLYMER HAVING HETEROAROMATIC RING DAIKIN INDUSTRIES, LTD. (JP) 2012-10-25 US disclosed
US-8236887-B2 Fluorine-containing polymer having heteroaromatic ring DAIKIN INDUSTRIES, LTD. (JP) 2012-08-07 US disclosed
US-8123983-B2 Actuator element DAIKIN INDUSTRIES, LTD. (JP) 2012-02-28 US disclosed
EP-2416488-A1 ELECTRODE FILM FOR POLYMER ACTUATOR ELEMENT, AND POLYMER ACTUATOR ELEMENT COMPRISING SAME Daikin Industries, Ltd. (JP) 2012-02-08 EP disclosed
US-20120018680-A1 ELECTRODE FILM FOR POLYMER ACTUATOR ELEMENT, AND POLYMER ACTUATOR ELEMENT COMPRISING THE SAME NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHONOLGY (JP) 2012-01-26 US disclosed
US-20100164330-A1 ACTUATOR ELEMENT DAIKIN INDUSTRIES, LTD (JP) 2010-07-01 US disclosed
US-20090105400-A1 Imidazolium side chains for example; for example polymers based on 1-methyl-3-(2H,9H,9H-perfluoro-3,6-dioxa-5-methyl-8-nonenyl)-imidazolium trifluoromethanesulfonate; polymer electrolytes for fuel cell, secondary battery, capacitor, dye-sensitized solar cell and electrochromic device DAIKIN INDUSTRIES, LTD. (JP) 2009-04-23 US disclosed
EP-1983008-A1 FLUORINE-CONTAINING POLYMER CONTAINING HETEROAROMATIC RING Daikin Industries, Ltd. (JP) 2008-10-22 EP disclosed
EP-1981034-A1 ACTUATOR ELEMENT Daikin Industries, Ltd. (JP) 2008-10-15 EP disclosed