Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | CASP3 | P42574 | 1/20 | 0.55 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.55 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.48 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 7/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13699096 | 1.00 | ALDH1A1 (0.55) | ALDH1A1LMNACASP3SENP8SENP6 | |
| SCHEMBL4236560 | 0.83 | SLC6A2 (0.67) | ALDH1A1LMNACASP3SENP8SENP6 | |
| SCHEMBL3458790 | 0.76 | SRD5A1 (0.59) | ALDH1A1LMNACASP3SENP8SENP6 | |
| SCHEMBL1977190 | 0.76 | ALDH1A1 (0.70) | ALDH1A1LMNACASP3SENP8SENP6 | |
| SCHEMBL13699366 | 0.76 | ALDH1A1 (0.60) | ALDH1A1LMNACASP3SENP8SENP6 | |
| SCHEMBL23497366 | 0.75 | ALDH1A1 (0.55) | ALDH1A1LMNACASP3SENP8SENP6 | |
| SCHEMBL17869370 | 0.75 | ALDH1A1 (0.55) | ALDH1A1LMNACASP3SENP8SENP6 | |
| SCHEMBL22664149 | 0.75 | ALDH1A1 (0.55) | ALDH1A1LMNACASP3SENP8SENP6 | |
| SCHEMBL17908097 | 0.75 | ALDH1A1 (0.64) | ALDH1A1LMNACASP3SENP8SENP6 | |
| SCHEMBL4226992 | 0.74 | ALDH1A1 (0.54) | ALDH1A1LMNACASP3SENP8SENP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090233910-A1 | Npy antagonists, preparation and uses | CEREP (FR) | 2009-09-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090233910-A1 | Npy antagonists, preparation and uses | NPY1R, NPY5R, NPY2R | ALDH1A1 4542/4885LMNA 2227/4885CASP3 3919/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.