SCHEMBL4236765

SCHEMBL4236765

CCC(=O)N(c1ccccc1)C1(C(=O)OC)CCN(C(C)CC(=O)O)CC1

nearest known ligand 0.63

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 14/20 0.63
OPRD1 P41143 4/20 0.63
OPRK1 P41145 2/20 0.63
CACNA1C Q13936 1/20 0.63
OPRL1 P41146 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20953915 0.93 CACNA1C (0.68) OPRM1OPRD1OPRK1CACNA1COPRL1
SCHEMBL11565239 0.89 OPRM1 (0.68) OPRM1OPRD1OPRK1CACNA1COPRL1
SCHEMBL9227658 0.88 OPRM1 (0.62) OPRM1OPRD1OPRK1CACNA1COPRL1
SCHEMBL11563405 0.88 OPRM1 (0.68) OPRM1OPRD1OPRK1CACNA1COPRL1
SCHEMBL15817257 0.87 OPRM1 (0.66) OPRM1OPRD1OPRK1CACNA1COPRL1
SCHEMBL18623777 0.83 OPRM1 (0.76) OPRM1OPRD1OPRK1CACNA1COPRL1
SCHEMBL8989441 0.82 OPRM1 (0.82) OPRM1OPRD1OPRK1CACNA1COPRL1
SCHEMBL2214001 0.81 OPRM1 (0.69) OPRM1OPRD1OPRK1CACNA1C
SCHEMBL1952247 0.81 CACNA1C (0.86) OPRM1OPRD1OPRK1CACNA1C
SCHEMBL11563541 0.80 OPRM1 (0.82) OPRM1OPRD1OPRK1CACNA1C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12133922-B2 Abuse resistant capsule R.P. SCHERER TECHNOLOGIES, LLC (US) 2024-11-05 US claimed
US-20220362160-A1 ABUSE RESISTANT CAPSULE R.P. SCHERER TECHNOLOGIES, LLC (US) 2022-11-17 US claimed
US-11464747-B2 Abuse resistant capsule R.P. SCHERER TECHNOLOGIES, LLC (US) 2022-10-11 US claimed
EP-3446681-B1 ABUSE RESISTANT CAPSULE SCHERER TECHNOLOGIES LLC R P (US) 2020-12-23 EP claimed
EP-2968129-B1 ABUSE RESISTANT CAPSULE SCHERER TECHNOLOGIES LLC R P (US) 2018-09-05 EP claimed
US-20140271835-A1 ABUSE RESISTANT CAPSULE ARES CAPITAL CORPORATION, AS COLLATERAL AGENT 2014-09-18 US claimed
EP-1515702-B1 ABUSE-PROTECTED ADMINISTRATION FORM GRUENENTHAL GMBH (DE) 2008-10-15 EP claimed
US-20050191244-A1 Abuse-resistant pharmaceutical dosage form GRUENENTHAL GMBH (DE) 2005-09-01 US claimed
US-20250345767-A1 METHODS AND DEVICES FOR GENERATING CORE-SHELL DROPLETS AND PARTICLES THE TRUSTEES OF PRINCETON UNIVERSITY (US) 2025-11-13 US disclosed
EP-3824878-B1 ABUSE RESISTANT CAPSULE SCHERER TECHNOLOGIES LLC R P (US) 2025-11-12 EP disclosed
US-12133922-B2 Abuse resistant capsule R.P. SCHERER TECHNOLOGIES, LLC (US) 2024-11-05 US disclosed
US-20240108726-A1 METHODS AND COMPOSITIONS FOR SELF-REGULATED RELEASE OF ACTIVE PHARMACEUTICAL INGREDIENT ACURA PHARMACEUTICALS, INC. (US) 2024-04-04 US disclosed
US-11857629-B2 Methods and compositions for self-regulated release of active pharmaceutical ingredient ACURA PHARMACEUTICALS, INC. (US) 2024-01-02 US disclosed
WO-2023239688-A1 METHODS AND DEVICES FOR GENERATING CORE-SHELL DROPLETS AND PARTICLES THE TRUSTEES OF PRINCETON UNIVERSITY (US) 2023-12-14 WO disclosed
US-20080248113-A1 ABUSE-PROOFED ORAL DOSAGE FORM GRUNENTHAL GMBH (DE) 2008-10-09 US disclosed
US-20070231268-A1 Methods and compositions for deterring abuse of orally administered pharmaceutical products ACURA PHARMACEUTICALS, INC. 2007-10-04 US disclosed
US-20060177380-A1 Methods and compositions for deterring abuse of orally administered pharmaceutical products ACURA PHARMACEUTICALS, INC. 2006-08-10 US disclosed
US-20060110327-A1 Methods and compositions for deterring abuse of orally administered pharmaceutical products ACURA PHARMACEUTICALS, INC. 2006-05-25 US disclosed
US-20050236741-A1 Process for the production of an abuse-proofed solid dosage form ENDO PHARMACEUTICALS, INC. 2005-10-27 US disclosed
US-20050191244-A1 Abuse-resistant pharmaceutical dosage form GRUENENTHAL GMBH (DE) 2005-09-01 US disclosed