SCHEMBL4236887

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4230013	0.89	PTGS2 (0.49)	MAPTNPC1PKMARCYP19A1
	SCHEMBL4233150	0.89	AR (0.60)	MAPTNPC1ARCYP19A1ALDH1A1
	SCHEMBL4237759	0.85	AR (0.56)	MAPTNPC1ARCYP19A1ALDH1A1
	SCHEMBL4233511	0.83	AR (0.70)	ARKDM4ESLC34A1
	SCHEMBL4232172	0.83	AR (0.54)	MAPTARCYP19A1ALDH1A1KDM4E
	SCHEMBL4239003	0.83	AR (0.54)	NPC1PKMARCYP19A1ALDH1A1
	SCHEMBL4234713	0.81	MAPT (0.54)	MAPTARALDH1A1SLC34A1RAB9A
	SCHEMBL4237455	0.81	AR (0.52)	NPC1ARCYP19A1ALDH1A1SLC34A1
	SCHEMBL4302858	0.80	AR (0.52)	MAPTARCHEK2ALDH1A1SLC34A1
	SCHEMBL4296323	0.80	AR (0.54)	MAPTARALDH1A1KDM4ESLC34A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.