SCHEMBL42370

SCHEMBL42370

O=C(O)CC1c2ccccc2-c2ccccc21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EGFR P00533 1/20 0.51
TSHR P16473 2/20 0.50
CYP1A2 P05177 1/20 0.50
HTR2A P28223 1/20 0.50
MAPT P10636 1/20 0.49
KMT2A Q03164 1/20 0.44
FABP7 O15540 1/20 0.44
FABP5 Q01469 1/20 0.44
HDAC3 O15379 1/20 0.44
HDAC4 P56524 1/20 0.44
HDAC7 Q8WUI4 1/20 0.44
HDAC8 Q9BY41 1/20 0.44
HDAC6 Q9UBN7 1/20 0.44
HDAC9 Q9UKV0 1/20 0.44
HDAC5 Q9UQL6 1/20 0.44
NCOR2 Q9Y618 1/20 0.44
HSD17B10 Q99714 1/20 0.43
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
AKR1B1 P15121 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL27729485 0.98 EGFR (0.50) EGFRTSHRCYP1A2HTR2AMAPT
SCHEMBL13084394 0.86 EPHX2 (0.47) EGFRTSHRCYP1A2HTR2AMAPT
SCHEMBL27503052 0.85 HTR2A (0.42) EGFRTSHRCYP1A2HTR2AMAPT
SCHEMBL11764926 0.83 EDNRB (0.47) EGFRTSHRCYP1A2HTR2AMAPT
SCHEMBL1568272 0.83 TSHR (0.50) TSHRCYP1A2HTR2AMAPTKMT2A
SCHEMBL27730470 0.81 MAPT (0.39) EGFRTSHRCYP1A2HTR2AMAPT
SCHEMBL8279094 0.81 POLB (0.50) TSHRCYP1A2HTR2AMAPTKMT2A
SCHEMBL2108892 0.81 TSHR (0.49) TSHRCYP1A2HTR2AMAPTKMT2A
SCHEMBL87862 0.81 TSHR (0.49) TSHRCYP1A2HTR2AMAPTKMT2A
SCHEMBL87863 0.81 HSD17B10 (0.59) TSHRCYP1A2HTR2AMAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 785 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4661890-A1 PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS Purdue Research Foundation (US) 2025-12-17 EP claimed
CN-119552144-A Compound for targeted degradation of tyrosinase and preparation method and application thereof 中国药科大学 2025-03-04 CN claimed
WO-2024167565-A1 PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS PURDUE RESEARCH FOUNDATION (US) 2024-08-15 WO claimed
EP-4380998-A2 METHOD OF SYNTHESIZING A MUCIN AND PRODUCT THEREOF Research Foundation Of The City University Of New York (US) 2024-06-12 EP claimed
CN-115636994-B Low-density polyethylene resin composition for film 中国石油天然气股份有限公司 2024-03-01 CN claimed
CN-117486835-A Cabazitaxel prodrug self-assembled nano preparation and preparation method and application thereof 沈阳药科大学 2024-02-02 CN claimed
CN-116120333-A Podophyllotoxin nano prodrug and preparation method and application thereof 沈阳药科大学 2023-05-16 CN claimed
WO-2023014875-A2 METHOD OF SYNTHESIZING A MUCIN AND PRODUCT THEREOF RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK (US) 2023-02-09 WO claimed
CN-111650315-B Method for detecting alcohol metabolites of butadiene by using fluorescence derivatization-high performance liquid chromatography 上海大学 2022-11-18 CN claimed
CN-113845775-B Preparation method of hyperbranched polymer modified boron nitride heat-conducting and insulating composite material 江南大学 2022-06-21 CN claimed
US-6797745-B1 Hot melt inks containing styrene or terpene polymers XEROX CORPORATION 2004-09-28 US claimed
US-20040039159-A1 Mimetic insect allatostatin analogs for insect control NACHMAN RONALD J (US) 2004-02-26 US claimed
WO-2003084919-A2 METHOD FOR PREPARING COMBRETASTATINS AVENTIS PHARMA S.A. (FR) 2003-10-16 WO claimed
US-20030161857-A1 Mimetic insect allatostatin analogs for insect control UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE 2003-08-28 US claimed
US-6492441-B2 DIAZONAPTHOQUINONESULFONYL-SUBSTITUTED POLYMER SUITABLE FOR USE IN ANTI-REFLECTIVE COATING OF A SEMICONDUCTOR DEVICE HYUNDAI ELECTRONICS INDUSTRIES CO., LTD. (KR) 2002-12-10 US claimed
US-20020120070-A1 Anti reflective coating polymers and the preparation method thereof HYUNDAI ELECTRONICS INDUSTRIES CO., LTD. (KR) 2002-08-29 US claimed
US-6368778-B1 FLUORENONE, FLUORENE, COUMARIN, NAPHTHALIC ACID IMIDE, PYRAZOLINE, OR ANTHRACENE IMAGE STABILIZER COMPOUNDS IN THE SILVER LAYER REDUCE IMAGE BROWNING; STABLE TO LIGHT AND HEAT OVER TIME PARTICULARLY UNDER LIGHT-BOX CONDITIONS EASTMAN KODAK COMPANY 2002-04-09 US claimed
WO-2000029010-A1 MIMETIC INSECT ALLATOSTATIN ANALOGS FOR INSECT CONTROL THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) 2000-05-25 WO claimed
US-5663030-A A PHENYL OR NORBORNANE DERIVATIVE AS AN ADDITIVE TO REDUCE HEAT AND ENERGY REQUIRED TO FUSE THE TONER AND TO REDUCE JAMMING OF THE EQUIPMENT XEROX CORPORATION (US) 1997-09-02 US claimed
US-5059679-A Using blocking agents SHIN-ETSU CHEMICAL CO., LTD. (JP) 1991-10-22 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040039159-A1 Mimetic insect allatostatin analogs for insect control ANPEP, CTRL, DNPEP EGFR 2645/4885TSHR 958/4885CYP1A2 4451/4885
US-20030161857-A1 Mimetic insect allatostatin analogs for insect control ANPEP, CTRL, DNPEP EGFR 2645/4885TSHR 958/4885CYP1A2 4451/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.