SCHEMBL42375

SCHEMBL42375

C=C1CC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11074596 0.94
SCHEMBL239887 0.94
SCHEMBL3440747 0.94
SCHEMBL2161449 0.84
SCHEMBL14481097 0.80
SCHEMBL17478307 0.80 TRIM24 (0.31)
SCHEMBL136351 0.76
SCHEMBL170119 0.73
SCHEMBL17533951 0.72
SCHEMBL8997440 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1849 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119219557-A Preparation method of beta, gamma-unsaturated nitrile compound 苏州大学 2024-12-31 CN claimed
EP-4389745-A1 PYRIDONE COMPOUND HAVING INTEGRASE INHIBITORY ACTIVITY AND PHARMACEUTICAL USE THEREOF Jiangsu Hengrui Pharmaceuticals Co., Ltd. (CN) 2024-06-26 EP claimed
CN-118201930-A WEE1 protein kinase degradation agent and application thereof 杭州格博生物医药有限公司 2024-06-14 CN claimed
EP-4375277-A1 LPA1 SMALL MOLECULE ANTAGONIST Tuojie Biotech (Shanghai) Co., Ltd. (CN) 2024-05-29 EP claimed
WO-2024107686-A1 MACROCYCLIC KRAS INHIBITORS AND METHODS OF USE AMGEN INC. (US) 2024-05-23 WO claimed
CN-118027260-A High-selectivity polymer material with adjustable repeating unit carbon skeleton structure and preparation method thereof 大连理工大学 2024-05-14 CN claimed
WO-2024088296-A1 PIPERIDINOPYRIMIDINE DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF IN MEDICINE 上海拓界生物医药科技有限公司 2024-05-02 WO claimed
CN-117886814-A PD-1/PD-L1 small molecule inhibitor and application thereof in medicines 广东东阳光药业股份有限公司 2024-04-16 CN claimed
CN-117715908-A Pyridone compounds having integrase inhibitory activity and their pharmaceutical use 江苏恒瑞医药股份有限公司 2024-03-15 CN claimed
WO-2024027814-A1 COMPOUND HAVING KRAS G12D INHIBITORY EFFECT 杭州中美华东制药有限公司 2024-02-08 WO claimed
WO-1995009826-A1 PROCESS FOR THE PREPARATION OF METHYLENECYCLOPROPANE STUDIENGESELLSCHAFT KOHLE MBH (DE) 1995-04-13 WO claimed
EP-0641356-A1 INHIBITORS OF 5-ALPHA-TESTOSTERONE REDUCTASE GLAXO WELLCOME INC. (US) 1995-03-08 EP claimed
WO-1994014833-A2 SUBSTITUTED 6-AZAANDROSTENONES GLAXO WELLCOME INC. (US) 1994-07-07 WO claimed
WO-1994000432-A1 ANORECTIC EPINEPHRINE DERIVATIVES THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 1994-01-06 WO claimed
WO-1993013124-A1 INHIBITORS OF 5-ALPHA-TESTOSTERONE REDUCTASE GLAXO INC. (US) 1993-07-08 WO claimed
EP-0152027-B1 PROCESS FOR THE PREPARATION OF 3-METHYL-2-BUTEN-4-OLIDE(4-METHYL-2-(5H)-FURAN-2-ONE) Studiengesellschaft Kohle mbH (DE) 1990-04-11 EP claimed
US-4659843-A Process for preparing 3-methyl-2-butene-4-olide (4-methyl-2(5H)-furane-2-one) STUDIENGESELLSCHAFT KOHLE MBH (DE) 1987-04-21 US claimed
US-4632996-A FORMING PI-ALLYL PALLADIUM COMPOUNDS IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) 1986-12-30 US claimed
EP-0152027-A2 Process for the preparation of 3-methyl-2-buten-4-olide(4-methyl-2-(5H)-furan-2-one) Studiengesellschaft Kohle mbH (DE) 1985-08-21 EP claimed
US-4242278-A Process for the preparation of 2-(2',2',2'-trihalogenoethyl)-4-halogenocyclobutan-1-ones CIBA-GEIGY CORPORATION (US) 1980-12-30 US claimed