Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 11/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 11/20 | 0.57 |
| ▸ | MAPT | P10636 | 11/20 | 0.57 |
| ▸ | GAA | P10253 | 10/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.57 |
| ▸ | RAB9A | P51151 | 7/20 | 0.57 |
| ▸ | NPC1 | O15118 | 7/20 | 0.57 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.57 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.57 |
| ▸ | RELA | Q04206 | 3/20 | 0.57 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.57 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4236943 | 0.80 | MEN1 (0.57) | MEN1KMT2AMAPTGAAALDH1A1 | |
| SCHEMBL1051258 | 0.80 | RECQL (0.44) | MEN1KMT2AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL2535401 | 0.77 | NPC1 (0.60) | MEN1KMT2AMAPTGAAALDH1A1 | |
| SCHEMBL2512904 | 0.77 | RAB9A (0.44) | MEN1KMT2AMAPTGAAALDH1A1 | |
| SCHEMBL370879 | 0.77 | MEN1 (0.44) | MEN1KMT2AMAPTGAAALDH1A1 | |
| SCHEMBL1048977 | 0.76 | RECQL (0.39) | MEN1KMT2AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL3354435 | 0.76 | NPC1 (0.58) | MEN1KMT2AMAPTGAAALDH1A1 | |
| SCHEMBL2510097 | 0.74 | NPC1 (0.56) | MEN1KMT2AMAPTGAAALDH1A1 | |
| SCHEMBL3354574 | 0.74 | NPC1 (0.56) | MEN1KMT2AMAPTGAAALDH1A1 | |
| SCHEMBL29276782 | 0.74 | MEN1 (1.00) | MEN1KMT2AMAPTGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009010871-A2 | PYRAZOLE DERIVATIVES AS ANTAGONISTS OF ADENOSINE A3 RECEPTOR | ADDEX PHARMA S.A. (CH) | 2009-01-22 | — | — | WO | disclosed |