Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3891072 | 0.76 | AKT1 (0.60) | AKT1AKT2 | |
| SCHEMBL3891901 | 0.74 | AKT1 (1.00) | AKT1AKT2 | |
| SCHEMBL3897323 | 0.73 | AKT1 (0.79) | AKT1AKT2 | |
| SCHEMBL3707264 | 0.73 | AKT1 (0.58) | AKT1AKT2 | |
| SCHEMBL3903351 | 0.73 | AKT1 (0.65) | AKT1AKT2 | |
| SCHEMBL13790596 | 0.71 | AKT1 (0.63) | AKT1AKT2 | |
| SCHEMBL3891081 | 0.71 | AKT1 (0.87) | AKT1AKT2 | |
| SCHEMBL2899272 | 0.71 | AKT1 (1.00) | AKT1AKT2 | |
| SCHEMBL3893836 | 0.70 | AKT1 (1.00) | AKT1AKT2 | |
| SCHEMBL2896614 | 0.70 | AKT1 (0.60) | AKT1AKT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1784175-A4 | INHIBITORS OF AKT ACTIVITY | MERCK & CO INC (US) | 2009-07-22 | — | — | EP | disclosed |
| EP-1784175-A2 | INHIBITORS OF AKT ACTIVITY | Merck & Co., Inc. (US) | 2007-05-16 | — | — | EP | disclosed |
| WO-2006036395-A2 | INHIBITORS OF AKT ACTIVITY | MERCK & CO., INC. (US) | 2006-04-06 | — | — | WO | disclosed |