Known targets — ChEMBL curated mechanism
ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4
The experimentally established mechanism targets of Benzoic Acid Hydrazide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 3/20 | 0.54 |
| ▸ | MPO | P05164 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | KDM5A | P29375 | 1/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
| ▸ | GFER | P55789 | 1/20 | 0.54 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | IDO1 | P14902 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid Hydrazide SCHEMBL11870297 | 0.92 | HDAC3 (0.60) | NR4A2GAAMPOCYP3A4KDM5A | |
| Benzoic Acid Hydrazide SCHEMBL11859930 | 0.92 | HDAC3 (0.55) | NR4A2GAAMPOCYP3A4KDM5A | |
| Benzoic Acid Hydrazide SCHEMBL4515671 | 0.91 | CYP3A4 (0.62) | GAAMPOCYP3A4KDM5ABLM | |
| Benzoic Acid Hydrazide SCHEMBL83514 | 0.91 | CYP3A4 (0.62) | GAAMPOCYP3A4KDM5ABLM | |
| SCHEMBL20078583 | 0.91 | CYP3A4 (0.62) | GAAMPOCYP3A4KDM5ABLM | |
| Octanedioate SCHEMBL11860281 | 0.90 | HDAC3 (0.63) | NR4A2GAAMPOCYP3A4KDM5A | |
| Benzoic Acid Hydrazide SCHEMBL15794721 | 0.90 | HDAC3 (0.63) | NR4A2GAAMPOCYP3A4KDM5A | |
| Azelaic Acid SCHEMBL11861583 | 0.90 | HDAC3 (0.63) | NR4A2GAAMPOCYP3A4KDM5A | |
| Sebacic Acid SCHEMBL3091757 | 0.90 | HDAC3 (0.63) | NR4A2GAAMPOCYP3A4KDM5A | |
| Benzoic Acid Hydrazide SCHEMBL11861698 | 0.89 | CYP3A4 (0.56) | GAAMPOCYP3A4KDM5ABLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120018088-A1 | METHOD FOR CONNECTING ELECTRODES AND BONDING COMPOSITION USED THEREFOR | HENKEL CORPORATION (US) | 2012-01-26 | — | — | US | disclosed |
| US-3954904-A | DICARBOXYLIC ACID DIHYDRAZIDE | MITSUBISHI GAS CHEMICAL CO., INC. (JA) | 1976-05-04 | — | — | US | disclosed |
| US-3952072-A | MOLDING MATERIALS | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JA) | 1976-04-20 | — | — | US | disclosed |