Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR5 | P35346 | 18/20 | 0.49 |
| ▸ | HRH1 | P35367 | 4/20 | 0.49 |
| ▸ | HTR2B | P41595 | 2/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3778980 | 0.95 | SSTR5 (0.53) | SSTR5HRH1HTR2BACHE | |
| SCHEMBL4231242 | 0.92 | SSTR5 (0.50) | SSTR5HRH1HTR2BKCNH2ACHE | |
| SCHEMBL4238563 | 0.89 | SSTR5 (0.51) | SSTR5HRH1HTR2B | |
| SCHEMBL4235419 | 0.87 | SSTR5 (0.54) | SSTR5HRH1HTR2BKCNH2 | |
| SCHEMBL4234199 | 0.87 | SSTR5 (0.54) | SSTR5HRH1HTR2BKCNH2 | |
| SCHEMBL4235821 | 0.87 | SSTR5 (0.44) | SSTR5HRH1HTR2BKCNH2ACHE | |
| SCHEMBL3781119 | 0.86 | SSTR5 (0.54) | SSTR5HRH1HTR2BKCNH2ACHE | |
| SCHEMBL4235753 | 0.84 | SSTR5 (0.45) | SSTR5HRH1HTR2BACHE | |
| SCHEMBL4224881 | 0.84 | SSTR5 (0.57) | SSTR5HRH1HTR2BKCNH2 | |
| SCHEMBL3782226 | 0.83 | SSTR5 (0.55) | SSTR5HRH1HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2001867-B1 | PYRIMIDINE, QUINAZOLINE, PTERIDINE AND TRIAZINE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2009-07-01 | — | — | EP | disclosed |