SCHEMBL4238445

SCHEMBL4238445

C=CCc1c(O)c(Oc2ccccc2)cc(Oc2ccccc2)c1O

nearest known ligand 0.43

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MMP2 P08253 1/20 0.43
TTR P02766 2/20 0.42
CAMK2A Q9UQM7 1/20 0.39
LTA4H P09960 1/20 0.37
NR1H2 P55055 1/20 0.37
BAX Q07812 1/20 0.37
XDH P47989 1/20 0.37
ALDH1A1 P00352 1/20 0.37
HPGD P15428 1/20 0.37
GLA P06280 1/20 0.36
GAA P10253 1/20 0.36
HTT P42858 1/20 0.36
RAB9A P51151 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11667005 0.80 TTR (0.42) MMP2TTRLTA4HNR1H2BAX
SCHEMBL29353656 0.75 TTR (0.66) MMP2TTRXDHALDH1A1HPGD
SCHEMBL15362201 0.75 HRH1 (0.37) TTRCAMK2ALTA4HGLAGAA
SCHEMBL278393 0.75 HRH1 (0.46) ALDH1A1HPGDGAA
SCHEMBL28347086 0.74 MAPT (0.49) TTRALDH1A1HPGDHTTSMN1; SMN2
SCHEMBL18094957 0.73 DPP4 (0.42) LTA4HALDH1A1HPGDGAA
SCHEMBL3726505 0.73 GAA (0.43) LTA4HALDH1A1HPGDGLAGAA
SCHEMBL11500020 0.73 DPP4 (0.63) ALDH1A1GAA
SCHEMBL10768769 0.72 CYP1A2 (0.42) TTRLTA4HGAASMN1; SMN2
SCHEMBL11276170 0.72 GAA (0.35) TTRLTA4HALDH1A1HPGDGLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0896963-B1 Methyl oxirane dibenzoylresorcinol UV absorbers MOMENTIVE PERFORMANCE MAT INC (US) 2009-10-21 EP disclosed
US-5959012-A COMPATIBILITY, SOLUBILITY, LOWER VOLATILITY, HIGHER MOLECULAR WEIGHT GENERAL ELECTRIC COMPANY (US) 1999-09-28 US disclosed
EP-0896963-A1 Methyl oxirane dibenzoylresorcinol UV absorbers GENERAL ELECTRIC COMPANY (US) 1999-02-17 EP disclosed