SCHEMBL11276170

SCHEMBL11276170

C=CCc1c(Oc2ccccc2)ccc(Br)c1Br

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.35
LMNA P02545 1/20 0.35
KMT2A Q03164 1/20 0.35
TTR P02766 3/20 0.35
DPP4 P27487 1/20 0.35
LTA4H P09960 1/20 0.34
TSHR P16473 1/20 0.34
HRH1 P35367 1/20 0.33
NTRK1 P04629 1/20 0.33
NTRK3 Q16288 1/20 0.33
NTRK2 Q16620 1/20 0.33
SLC6A4 P31645 2/20 0.33
SRD5A1 P18405 1/20 0.33
GLA P06280 1/20 0.33
HTT P42858 1/20 0.33
RAB9A P51151 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
HTR6 P50406 1/20 0.33
RIPK1 Q13546 1/20 0.33
SLC6A2 P23975 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL754642 0.75 LTA4H (0.46) GAALMNAKMT2ATTRLTA4H
SCHEMBL10768769 0.74 CYP1A2 (0.42) GAALMNAKMT2ATTRDPP4
SCHEMBL278393 0.73 HRH1 (0.46) GAALMNAKMT2ADPP4TSHR
SCHEMBL11500020 0.72 DPP4 (0.63) GAALMNAKMT2ADPP4HRH1
SCHEMBL3726505 0.72 GAA (0.43) GAALMNAKMT2ADPP4LTA4H
SCHEMBL11667005 0.72 TTR (0.42) GAALMNAKMT2ATTRDPP4
SCHEMBL18094957 0.72 DPP4 (0.42) GAALMNAKMT2ADPP4LTA4H
SCHEMBL4238445 0.72 MMP2 (0.43) GAATTRLTA4HGLAHTT
SCHEMBL15362201 0.71 HRH1 (0.37) GAALMNAKMT2ATTRDPP4
SCHEMBL30083973 0.70 HRH1 (0.55) GAALMNAKMT2ATSHRHRH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4366279-A BROMO COMPOUNDS IDEMITSU KOSAN COMPANY LIMITED (JP) 1982-12-28 US disclosed