Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2492286 | 0.80 | CYP19A1 (0.34) | CYP19A1 | |
| SCHEMBL435414 | 0.71 | — | — | |
| SCHEMBL3242470 | 0.70 | CYP19A1 (0.37) | CYP19A1 | |
| SCHEMBL1119818 | 0.66 | CYP19A1 (0.36) | CYP19A1 | |
| SCHEMBL2398838 | 0.65 | CYP19A1 (0.30) | CYP19A1 | |
| SCHEMBL10536064 | 0.65 | GSK3B (0.32) | — | |
| SCHEMBL31285568 | 0.62 | CYP19A1 (0.34) | CYP19A1 | |
| SCHEMBL1059783 | 0.61 | — | — | |
| SCHEMBL5433994 | 0.59 | — | — | |
| SCHEMBL3475574 | 0.56 | GSK3B (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009111547-A1 | 7H-PYRROLO[2,3-H]QUINAZOLINE COMPOUNDS, THEIR USE AS MTOR KINASE AND PI3 KINASE INHIBITORS, AND THEIR SYNTHESIS | WYETH (US) | 2009-09-11 | — | — | WO | disclosed |