Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HNF4A | P41235 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6293659 | 0.90 | TSHR (0.38) | TSHRHSP90AA1HNF4AALDH1A1SMN1; SMN2 | |
| SCHEMBL9565733 | 0.87 | TSHR (0.30) | TSHR | |
| SCHEMBL9820279 | 0.81 | TSHR (0.35) | TSHRHSP90AA1HNF4AALDH1A1SMN1; SMN2 | |
| SCHEMBL9820250 | 0.77 | SMN1; SMN2 (0.40) | TSHRALDH1A1SMN1; SMN2TDP1GAA | |
| SCHEMBL211655 | 0.75 | HTT (0.39) | TSHRHSP90AA1HNF4AALDH1A1SMN1; SMN2 | |
| SCHEMBL7521032 | 0.75 | TDP1 (0.30) | TDP1 | |
| SCHEMBL8849833 | 0.74 | SNCA (0.38) | TSHRHSP90AA1HNF4AALDH1A1GAA | |
| SCHEMBL198863 | 0.74 | ALDH1A1 (0.44) | TSHRHSP90AA1HNF4AALDH1A1SMN1; SMN2 | |
| SCHEMBL1933923 | 0.73 | TSHR (0.47) | TSHRHSP90AA1HNF4AALDH1A1TDP1 | |
| SCHEMBL10580043 | 0.73 | ALDH1A1 (0.35) | TSHRALDH1A1SMN1; SMN2TDP1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0547414-A2 | Process for the preparation of N-substituted nitro-p-phenylenediamines | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-06-23 | — | — | EP | claimed |
| WO-2009013779-A2 | SUBSTANTIVE PHOTOSTABLE DYES AND METHOD FOR THE PRODUCTION THEREOF | UNIVERSITA' DEGLI STUDI DI SIENA (IT) | 2009-01-29 | — | — | WO | disclosed |
| US-20080276384-A1 | HAIR DYE COMPOSITIONS | ARIMINO CO., LTD. (JP) | 2008-11-13 | — | — | US | disclosed |
| US-6368360-B2 | A DIRECT DYE CONTAINING QUATERNARY AMMONIUM SALT IS MIXED WITH AN OXIDIZING AGENT AT BASIC PH AT THE TIME OF DYEING OF KERATIN FIBERS, IN PARTICULAR THE HAIR | L'OREAL S.A. (FR) | 2002-04-09 | — | — | US | disclosed |
| US-20010001333-A1 | DYE COMPOSITION FOR KERATIN FIBRES COMPRISING A SPECIFIC DIRECT DYE | HENRI SAMAIN | 2001-05-24 | — | — | US | disclosed |
| EP-0743848-B1 | 2-FLUORO-6-NITROANILINES | HENKEL KGAA (DE) | 2000-11-08 | — | — | EP | disclosed |
| US-5980587-A | APPLYING DYE MIXTURE COMPRISING DIRECT DYE, OXIDIZING AGENT AND BASIFICATION AGENT TO KERATIN FIBERS SUCH AS HAIR | L'OREAL (FR) | 1999-11-09 | — | — | US | disclosed |
| EP-0648204-B1 | AMINO DEOXYALDITOL LIPOPHILIC DERIVATIVES FOR USE IN COSMETICS, COSMETIC COMPOSITIONS CONTAINING SAME AND NOVEL ALKYL CARBAMATES | OREAL (FR) | 1998-11-18 | — | — | EP | disclosed |
| EP-0810851-A1 | ENLIGHTNING DYEING COMPOSITION FOR KERATINIC FIBRES COMPRISING A DIRECT SPECIFIC DYE | L'OREAL (FR) | 1997-12-10 | — | — | EP | disclosed |
| WO-1997020545-A1 | ENLIGHTNING DYEING COMPOSITION FOR KERATINIC FIBRES COMPRISING A DIRECT SPECIFIC DYE | L'OREAL (FR) | 1997-06-12 | — | — | WO | disclosed |
| EP-0648204-A1 | AMINO DEOXYALDITOL LIPOPHILIC DERIVATIVES FOR USE IN COSMETICS, COSMETIC COMPOSITIONS CONTAINING SAME AND NOVEL ALKYL CARBAMATES | L'OREAL (FR) | 1995-04-19 | — | — | EP | disclosed |
| WO-1994024097-A1 | AMINO DEOXYALDITOL LIPOPHILIC DERIVATIVES FOR USE IN COSMETICS, COSMETIC COMPOSITIONS CONTAINING SAME AND NOVEL ALKYL CARBAMATES | L'OREAL (FR) | 1994-10-27 | — | — | WO | disclosed |
| EP-0547414-A2 | Process for the preparation of N-substituted nitro-p-phenylenediamines | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-06-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010001333-A1 | DYE COMPOSITION FOR KERATIN FIBRES COMPRISING A SPECIFIC DIRECT DYE | KRT18, IK, CYBA | TSHR 4684/4885HSP90AA1 2732/4885HNF4A 3471/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.