Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.68 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 3/20 | 0.39 |
| ▸ | HTR7 | P34969 | 3/20 | 0.39 |
| ▸ | HTR2B | P41595 | 3/20 | 0.39 |
| ▸ | HTR3A | P46098 | 3/20 | 0.39 |
| ▸ | HTR6 | P50406 | 3/20 | 0.39 |
| ▸ | HTR1D | P28221 | 2/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.39 |
| ▸ | CDC42BPB | Q9Y5S2 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30073656 | 0.94 | ALDH1A1 (0.75) | ALDH1A1MAPTLMNAGAASMN1; SMN2 | |
| SCHEMBL8295259 | 0.94 | ALDH1A1 (0.75) | ALDH1A1MAPTLMNAGAASMN1; SMN2 | |
| SCHEMBL20140512 | 0.83 | ALDH1A1 (0.68) | ALDH1A1MAPTLMNAGAASMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL3919226 | 0.82 | ALDH1A1 (0.60) | ALDH1A1MAPTLMNAGAASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL20140912 | 0.81 | ALDH1A1 (0.66) | ALDH1A1MAPTLMNAGAASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL20140001 | 0.81 | ALDH1A1 (0.66) | ALDH1A1MAPTLMNAGAASMN1; SMN2 | |
| SCHEMBL25629584 | 0.79 | ALDH1A1 (0.52) | ALDH1A1MAPTLMNAGAASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL31720538 | 0.78 | ALDH1A1 (0.51) | ALDH1A1MAPTLMNAGAASMN1; SMN2 | |
| SCHEMBL8433491 | 0.77 | ALDH1A1 (0.64) | ALDH1A1MAPTLMNAHTR7HTR3A | |
| SCHEMBL8437165 | 0.77 | ALDH1A1 (0.64) | ALDH1A1MAPTLMNAGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090233910-A1 | Npy antagonists, preparation and uses | CEREP (FR) | 2009-09-17 | — | — | US | disclosed |
| EP-1879887-A2 | NPY ANTAGONISTS, PREPARATION AND USE | Cerep (FR) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006108965-A2 | NPY ANTAGONISTS, PREPARATION AND USE | CEREP (FR) | 2006-10-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090233910-A1 | Npy antagonists, preparation and uses | NPY1R, NPY5R, NPY2R | ALDH1A1 4542/4885MAPT 1398/4885LMNA 2227/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.