Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.49 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 7/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP12 | P39900 | 1/20 | 0.42 |
| ▸ | HMGCR | P04035 | 2/20 | 0.39 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10755328 | 0.89 | FFAR1 (0.60) | FFAR1FFAR4KCNH2MMP2MMP12 | |
| SCHEMBL4240942 | 0.84 | FFAR1 (0.52) | FFAR1FFAR4KCNH2MMP2MMP12 | |
| SCHEMBL8387466 | 0.81 | FFAR1 (0.48) | FFAR1FFAR4KCNH2MMP2MMP12 | |
| SCHEMBL15283934 | 0.80 | KCNH2 (0.47) | FFAR1FFAR4KCNH2MMP2MMP12 | |
| SCHEMBL14252030 | 0.76 | FFAR1 (0.60) | FFAR1FFAR4MMP2MMP12HMGCR | |
| SCHEMBL5886652 | 0.75 | FFAR1 (0.63) | FFAR1FFAR4KCNH2MMP2MMP12 | |
| SCHEMBL2023915 | 0.73 | FFAR1 (0.70) | FFAR1FFAR4KCNH2MMP2MMP12 | |
| SCHEMBL9332907 | 0.73 | FFAR1 (0.61) | FFAR1FFAR4KCNH2MMP2MMP12 | |
| SCHEMBL9335934 | 0.73 | FFAR1 (0.61) | FFAR1FFAR4KCNH2MMP2MMP12 | |
| SCHEMBL9333090 | 0.73 | FFAR1 (0.61) | FFAR1FFAR4KCNH2MMP2MMP12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2059496-A1 | ACETYLENIC COMPOUNDS | Commonwealth Scientific and Industrial Research Organisation (AU) | 2009-05-20 | — | — | EP | disclosed |
| WO-2008031157-A1 | ACETYLENIC COMPOUNDS | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2008-03-20 | — | — | WO | disclosed |