Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K1 | Q02750 | 2/20 | 0.42 |
| ▸ | IKBKB | O14920 | 2/20 | 0.41 |
| ▸ | CHUK | O15111 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | IRAK4 | Q9NWZ3 | 4/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | JAK1 | P23458 | 1/20 | 0.37 |
| ▸ | JAK3 | P52333 | 1/20 | 0.37 |
| ▸ | ACP1 | P24666 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | SYK | P43405 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3324472 | 0.91 | EED (0.43) | MAP2K1IKBKBCHUKSLC6A2SLC6A4 | |
| SCHEMBL3324465 | 0.91 | EED (0.43) | MAP2K1IKBKBCHUKSLC6A2SLC6A4 | |
| SCHEMBL3328810 | 0.89 | MAP2K1 (0.43) | MAP2K1IKBKBCHUKSLC6A4KDM1A | |
| SCHEMBL3324733 | 0.89 | MAP2K1 (0.43) | MAP2K1IKBKBCHUKSLC6A4KDM1A | |
| SCHEMBL3323670 | 0.88 | IKBKB (0.43) | MAP2K1IKBKBCHUKSLC6A2SLC6A4 | |
| SCHEMBL3324255 | 0.88 | IKBKB (0.43) | MAP2K1IKBKBCHUKSLC6A2SLC6A4 | |
| SCHEMBL3325306 | 0.88 | S1PR4 (0.45) | MAP2K1IKBKBCHUKSLC6A2SLC6A4 | |
| SCHEMBL3325855 | 0.88 | S1PR4 (0.45) | MAP2K1IKBKBCHUKSLC6A2SLC6A4 | |
| SCHEMBL3325140 | 0.86 | MAP2K1 (0.41) | MAP2K1IKBKBCHUKSLC6A2SLC6A4 | |
| SCHEMBL3325149 | 0.86 | MAP2K1 (0.41) | MAP2K1IKBKBCHUKSLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2066630-A1 | PIPERIDINE DERIVATIVES | Pfizer Products Incorporated (US) | 2009-06-10 | — | — | EP | disclosed |
| WO-2008023258-A1 | PIPERIDINE DERIVATIVES | PFIZER PRODUCTS INC. (US) | 2008-02-28 | — | — | WO | disclosed |