SCHEMBL4239107

SCHEMBL4239107

CCOC(=O)c1cccc(C(C)=O)c1O

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.63
CA12 O43570 3/20 0.55
CA1 P00915 3/20 0.55
CA2 P00918 3/20 0.55
CA7 P43166 3/20 0.55
CA9 Q16790 3/20 0.55
CA14 Q9ULX7 3/20 0.55
ALDH1A1 P00352 3/20 0.54
HSD17B10 Q99714 1/20 0.54
GAA P10253 4/20 0.50
CDC25B P30305 3/20 0.50
MAPT P10636 3/20 0.50
CLEC4M Q9H2X3 1/20 0.50
CYP1A2 P05177 2/20 0.49
NPC1 O15118 1/20 0.47
POLB P06746 1/20 0.47
KMT2A Q03164 2/20 0.47
HPGD P15428 1/20 0.47
LMNA P02545 1/20 0.47
CDC25A P30304 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10571657 0.93 TSHR (0.73) TSHRCA12CA1CA2CA7
SCHEMBL11052918 0.86 TSHR (0.63) TSHRCA12CA1CA2CA7
SCHEMBL8587599 0.86 TSHR (0.44) TSHRALDH1A1HSD17B10GAANPC1
SCHEMBL4221271 0.84 TSHR (0.43) TSHRALDH1A1HSD17B10GAANPC1
SCHEMBL8875607 0.84 TSHR (0.61) TSHRCA12CA1CA2CA7
SCHEMBL1242911 0.84 GAA (0.66) TSHRCA12CA1CA2CA7
SCHEMBL340364 0.84 CA12 (0.67) TSHRCA12CA1CA2CA7
SCHEMBL3945626 0.83 TSHR (0.84) TSHRALDH1A1HSD17B10GAACDC25B
SCHEMBL23803712 0.83 TSHR (0.59) TSHRCA12CA1CA2CA7
SCHEMBL7848703 0.82 TSHR (0.63) TSHRCA12CA1CA2CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115312230-B Conductive silver paste, preparation method and application thereof 无锡帝科电子材料股份有限公司 2025-06-24 CN claimed
CN-117417914-A Marker for preventing and protecting cerebral ischemia diseases and application of aspirin derivative in preventing and protecting cerebral ischemia diseases 华东师范大学 2024-01-19 CN claimed
CN-117059304-A Conductive paste, preparation method thereof and electronic device 广东爱旭科技有限公司 2023-11-14 CN claimed
CN-115312230-A Conductive silver paste, and preparation method and application thereof 无锡帝科电子材料股份有限公司 2022-11-08 CN claimed
WO-2022228297-A1 ENZYMATIC PREPARATION TECHNIQUE FOR ACYL/AROYL COENZYME A 中国医学科学院药物研究所 2022-11-03 WO claimed
CN-115247192-A Enzymatic preparation technology of acyl/aroyl coenzyme A 中国医学科学院药物研究所 2022-10-28 CN claimed
US-10191398-B2 Electrophotographic photoconductor, image forming apparatus, and process cartridge RICOH COMPANY, LTD. (JP) 2019-01-29 US claimed
EP-1278517-B1 METHODS FOR IMPROVING SIZE AND APPEARANCE OF A WOUND AVOCET POLYMER TECHNOLOGIES IN (US) 2007-05-30 EP claimed
EP-1278517-A2 METHODS FOR IMPROVING SIZE AND APPEARANCE OF A WOUND Avocet Polymer Technologies, Inc. (US) 2003-01-29 EP claimed
US-20020013300-A1 Methods for improving size and appearance of a wound AVOCET POLYMER TECHNOLOGIES, INC. (US) 2002-01-31 US claimed
WO-2001070210-A2 METHODS FOR IMPROVING SIZE AND APPEARANCE OF A WOUND AVOCET POLYMER TECHNOLOGIES, INC. (US) 2001-09-27 WO claimed
US-4244948-A Medical use of esters of acetylsalicylic acid to treat acne ALLERGAN PHARMACEUTICALS, INC. (US) 1981-01-13 US claimed
CN-115312230-B Conductive silver paste, preparation method and application thereof 无锡帝科电子材料股份有限公司 2025-06-24 CN disclosed
CN-116646111-B Conductive silver-aluminum paste and preparation method and application thereof 无锡帝科电子材料股份有限公司 2024-10-29 CN disclosed
WO-2024016944-A1 MARKER FOR PREVENTING AND PROTECTING AGAINST CEREBRAL ISCHEMIC DISEASES AND APPLICATION OF ASPIRIN DERIVATIVE IN PREVENTING AND PROTECTING AGAINST CEREBRAL ISCHEMIC DISEASES 华东师范大学 2024-01-25 WO disclosed
CN-117417914-A Marker for preventing and protecting cerebral ischemia diseases and application of aspirin derivative in preventing and protecting cerebral ischemia diseases 华东师范大学 2024-01-19 CN disclosed
US-5474994-A Treating hypertension, urethral and lower urinary tract contractions RECORDATI S.A., CHEMICAL AND PHARMACEUTICAL COMPANY (CH) 1995-12-12 US disclosed
WO-1993017007-A1 HETEROBICYCLIC COMPOUNDS RECORDATI INDUSTRIA CHIMICA E FARMACEUTICA S.P.A. (IT) 1993-09-02 WO disclosed
EP-0558245-A1 Heterobicyclic compounds as antagogists of alpha-1 adrenergic and SHT1A receptors RECORDATI S.A. CHEMICAL and PHARMACEUTICAL COMPANY (CH) 1993-09-01 EP disclosed
US-4244948-A Medical use of esters of acetylsalicylic acid to treat acne ALLERGAN PHARMACEUTICALS, INC. (US) 1981-01-13 US disclosed