Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR5 | P35346 | 4/20 | 0.48 |
| ▸ | EHMT2 | Q96KQ7 | 8/20 | 0.47 |
| ▸ | EHMT1 | Q9H9B1 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | KDM1A | O60341 | 2/20 | 0.46 |
| ▸ | RCOR1 | Q9UKL0 | 2/20 | 0.46 |
| ▸ | NSD2 | O96028 | 3/20 | 0.44 |
| ▸ | HRH1 | P35367 | 2/20 | 0.44 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | DNMT3A | Q9Y6K1 | 2/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3782678 | 0.95 | EHMT2 (0.51) | SSTR5EHMT2EHMT1ALDH1A1HPGD | |
| SCHEMBL4232529 | 0.93 | SSTR5 (0.48) | SSTR5EHMT2EHMT1ALDH1A1HPGD | |
| SCHEMBL4220575 | 0.93 | EHMT2 (0.47) | SSTR5EHMT2EHMT1ALDH1A1HPGD | |
| SCHEMBL4231531 | 0.93 | EHMT2 (0.48) | SSTR5EHMT2EHMT1ALDH1A1HPGD | |
| SCHEMBL4222867 | 0.91 | EHMT2 (0.49) | SSTR5EHMT2EHMT1ALDH1A1HPGD | |
| SCHEMBL4235382 | 0.91 | ALDH1A1 (0.47) | SSTR5EHMT2EHMT1ALDH1A1HPGD | |
| SCHEMBL4234599 | 0.90 | SSTR5 (0.51) | SSTR5EHMT2EHMT1ALDH1A1HPGD | |
| SCHEMBL4223216 | 0.88 | SSTR5 (0.48) | SSTR5EHMT2KDM1ARCOR1HRH1 | |
| SCHEMBL3776411 | 0.88 | EHMT2 (0.51) | SSTR5EHMT2EHMT1ALDH1A1HPGD | |
| SCHEMBL3782683 | 0.88 | EHMT2 (0.51) | SSTR5EHMT2EHMT1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2001867-B1 | PYRIMIDINE, QUINAZOLINE, PTERIDINE AND TRIAZINE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2009-07-01 | — | — | EP | disclosed |