SCHEMBL4239444

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL13805579	0.75	HTR2C (0.55)	PPARDPTPN1HSD17B10KDM4ETP53
	SCHEMBL13422488	0.75	PTPN1 (0.43)	PTPN1HSD17B10MEN1LMNAKMT2A
	SCHEMBL15620453	0.74	KDM4E (0.36)	PTPN1HSD17B10MEN1LMNAKMT2A
	SCHEMBL5365370	0.74	PPARD (0.38)	PPARDPTPN1HSD17B10KDM4ETP53
	SCHEMBL4234524	0.73	PTPN1 (0.53)	PTPN1HSD17B10IDO1PDE4D
	SCHEMBL8679971	0.72	MAPT (0.53)	HSD17B10MEN1LMNAKMT2AKDM4E
	SCHEMBL8133127	0.72	ALDH1A1 (0.50)	PPARDPTPN1HSD17B10MEN1LMNA
	SCHEMBL30937310	0.72	ALDH1A1 (0.50)	PPARDPTPN1HSD17B10MEN1LMNA
	SCHEMBL16844642	0.69	PTPN1 (0.43)	PTPN1HSD17B10MEN1LMNAKMT2A
	SCHEMBL30277636	0.68	PTPN1 (0.48)	PPARDPTPN1MEN1LMNAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.