⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL425451 | 0.88 | — | — | |
| SCHEMBL429506 | 0.88 | — | — | |
| SCHEMBL427553 | 0.86 | EPHX1 (0.64) | — | |
| SCHEMBL7876971 | 0.86 | EPHX1 (0.64) | — | |
| SCHEMBL4670043 | 0.82 | EPHX1 (0.67) | — | |
| SCHEMBL3872513 | 0.82 | ALDH1A1 (0.37) | — | |
| SCHEMBL1176978 | 0.82 | EPHX1 (0.61) | — | |
| SCHEMBL5034033 | 0.82 | EPHX1 (0.39) | — | |
| SCHEMBL15796814 | 0.78 | KDM4E (0.43) | — | |
| SCHEMBL2224304 | 0.78 | EPHX2 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 462 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240239759-A1 | ISOXAZOLINE COMPOSITIONS AND THEIR USE AS ANTIPARASITICS | INTERVET INC. (US) | 2024-07-18 | — | — | US | claimed |
| EP-4399212-A1 | SUBSTITUTED 2,3-DIHYDRO[1,3]THIAZOLO[4,5-B]PYRIDINES, SALTS THEREOF AND THEIR USE AS HERBICIDALLY ACTIVE SUBSTANCES | Bayer Aktiengesellschaft (DE) | 2024-07-17 | — | — | EP | claimed |
| CN-118159542-A | Substituted 2, 3-dihydro [1,3] thiazolo [4,5-b ] pyridines, salts thereof and their use as herbicidal agents | 拜耳公司 | 2024-06-07 | — | — | CN | claimed |
| CN-111295376-B | Injectable isoxazoline pharmaceutical composition and use thereof against parasite infestations | 英特维特国际股份有限公司 | 2024-05-24 | — | — | CN | claimed |
| EP-4358941-A1 | PALATABLE VETERINARY COMPOSITIONS | Intervet International B.V. (NL) | 2024-05-01 | — | — | EP | claimed |
| US-20240122849-A1 | ISOXAZOLINE COMPOSITIONS AND USE THEREOF IN THE PREVENTION OR TREATMENT OF PARASITE INFESTATIONS IN ANIMALS | INTERVET INC. (US) | 2024-04-18 | — | — | US | claimed |
| EP-4351341-A1 | TICK CONTROL METHODS | Intervet International B.V. (NL) | 2024-04-17 | — | — | EP | claimed |
| CN-117545473-A | Palatable veterinary compositions | 英特维特国际股份有限公司 | 2024-02-09 | — | — | CN | claimed |
| EP-4316522-A2 | INJECTABLE ISOXAZOLINE PHARMACEUTICAL COMPOSITIONS AND THEIR USE AGAINST PARASITE INFESTATION | Intervet International B.V. (NL) | 2024-02-07 | — | — | EP | claimed |
| EP-4306168-A2 | ISOXAZOLINE COMPOSITIONS AND USE THEREOF IN THE PREVENTION OR TREATMENT OF PARASITE INFESTATIONS IN ANIMALS | Intervet International B.V. (NL) | 2024-01-17 | — | — | EP | claimed |
| WO-2007070818-A1 | SIX-MEMBERED HETEROCYCLES USEFUL AS SERINE PROTEASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-06-21 | — | — | WO | claimed |
| WO-2007070816-A2 | THIOPHENE DERIVATIVES AS FACTOR XIA INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-06-21 | — | — | WO | claimed |
| WO-2007070826-A1 | ARYLPROPIONAMIDE, ARYLACRYLAMIDE, ARYLPROPYNAMIDE, OR ARYLMETHYLUREA ANALOGS AS FACTOR XIA INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-06-21 | — | — | WO | claimed |
| JP-2007500725-A | — | — | 2007-01-18 | — | — | JP | claimed |
| CN-1860118-A | Compounds and compositions as protein kinase inhibitors | IRM LLC (BM) | 2006-11-08 | — | — | CN | claimed |
| EP-1651648-A2 | COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS | IRM LLC (BM) | 2006-05-03 | — | — | EP | claimed |
| US-20050222177-A1 | Compounds and compositions as protein kinase inhibitors | IRM LLC (BM) | 2005-10-06 | — | — | US | claimed |
| US-20050043315-A1 | Aminopyrimidine compounds, processes for their preparation and pharmaceutical compositions containing them | ASTELLAS PHARMA INC. (JP) | 2005-02-24 | — | — | US | claimed |
| WO-2005011597-A2 | COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS | IRM LLC (BM) | 2005-02-10 | — | — | WO | claimed |
| WO-2003057689-A1 | AMINOPYRIMIDINE COMPOUNDS, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-07-17 | — | — | WO | claimed |