Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13930302 | 0.87 | ABL1 (0.37) | PTGS2ABL1TSHRALDH1A1PDE3B | |
| SCHEMBL9079083 | 0.77 | ABL1 (0.42) | PTGS2ABL1TSHRALDH1A1PDE3B | |
| SCHEMBL3436908 | 0.77 | ABL1 (0.42) | PTGS2ABL1TSHRALDH1A1PDE3B | |
| SCHEMBL18299405 | 0.77 | ALDH1A1 (0.40) | PTGS2ABL1TSHRALDH1A1PDE3B | |
| SCHEMBL17681680 | 0.76 | AKR1B1 (0.49) | PTGS2ABL1TSHRALDH1A1PDE3B | |
| SCHEMBL18298886 | 0.76 | ABL1 (0.41) | PTGS2ABL1TSHRALDH1A1PDE3B | |
| SCHEMBL8307454 | 0.76 | ABL1 (0.41) | PTGS2ABL1TSHRALDH1A1PDE3B | |
| SCHEMBL3437074 | 0.75 | TSHR (0.40) | PTGS2ABL1TSHRALDH1A1PDE3B | |
| SCHEMBL8145311 | 0.75 | ABL1 (0.41) | PTGS2ABL1TSHRALDH1A1PDE3B | |
| SCHEMBL3193263 | 0.75 | ABL1 (0.41) | PTGS2ABL1TSHRALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090042730-A1 | Substituted Arylketones | HERRMANN STEFAN | 2009-02-12 | — | — | US | disclosed |
| US-7456133-B2 | Substituted arylketones | BAYER CROPSCIENCE AG (DE) | 2008-11-25 | — | — | US | disclosed |
| US-20060252647-A1 | Herbicides; broad active spectrum; on soil and above ground plant parts use | HERRMANN STEFAN | 2006-11-09 | — | — | US | disclosed |
| US-7112554-B2 | Substituted arylketones | BAYER CROPSCIENCE AG (DE) | 2006-09-26 | — | — | US | disclosed |
| US-20040176253-A1 | Substitued arylketones | BAYER CROPSCIENCE AG (DE) | 2004-09-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060252647-A1 | Herbicides; broad active spectrum; on soil and above ground plant parts use | CYP1A1, CYP1A2, CYP4X1 | PTGS2 1988/4885ABL1 893/4885TSHR 1785/4885 |
| US-20040176253-A1 | Substitued arylketones | CYP1B1, CYP1A1, CYP2E1 | PTGS2 3744/4885ABL1 132/4885TSHR 1625/4885 |
| US-20090042730-A1 | Substituted Arylketones | CYP1A1, CYP1B1, CYP1A2 | PTGS2 3299/4885ABL1 152/4885TSHR 1054/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.