SCHEMBL4239886

SCHEMBL4239886

Cc1nccn1C.Cc1nccn1CC(C)C

nearest known ligand 0.49

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.49
ALDH1A1 P00352 2/20 0.49
POLB P06746 2/20 0.49
BRD4 O60885 1/20 0.48
MAPT P10636 1/20 0.46
AGER Q15109 1/20 0.46
MEN1 O00255 2/20 0.42
HPGD P15428 1/20 0.42
TSHR P16473 1/20 0.41
KDM4E B2RXH2 1/20 0.40
CA12 O43570 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA9 Q16790 1/20 0.39
FDPS P14324 1/20 0.38
LMNA P02545 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL179780 0.91 KMT2A (0.52) KMT2AALDH1A1POLBBRD4MAPT
SCHEMBL7262138 0.79 ALDH1A1 (0.58) KMT2AALDH1A1POLBMAPTAGER
SCHEMBL8089526 0.79 ALDH1A1 (0.38) KMT2AALDH1A1POLBMAPTMEN1
SCHEMBL16694847 0.78
SCHEMBL15149 0.78
Iodide SCHEMBL1514189 0.76
Bromide SCHEMBL8202839 0.76
SCHEMBL30859446 0.76
Hydrochloric Acid SCHEMBL820275 0.76
SCHEMBL28562031 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1542082-B1 Electrophotographic photoreceptor, undercoat layer coating liquid therefor, method of preparing the photoreceptor, and image forming apparatus and process cartridge using the photoreceptor RICOH KK (JP) 2009-07-29 EP disclosed
EP-1542082-A1 Electrophotographic photoreceptor, undercoat layer coating liquid therefor, method of preparing the photoreceptor, and image forming apparatus and process cartridge using the photoreceptor Ricoh Company, Ltd. (JP) 2005-06-15 EP disclosed