SCHEMBL4240265

SCHEMBL4240265

Cl/C=C\C#Cc1ccco1

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.34
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4240268 1.00 ALOX5 (0.34) ALOX5ALDH1A1
SCHEMBL19475520 0.75
SCHEMBL1799185 0.75 ALOX5 (0.43) ALOX5ALDH1A1
SCHEMBL5517928 0.71 ALOX5 (0.44) ALOX5ALDH1A1
SCHEMBL11911403 0.68 ALOX5 (0.38) ALOX5
SCHEMBL1048506 0.67
SCHEMBL11911410 0.67
SCHEMBL18244837 0.67
SCHEMBL7109005 0.67
SCHEMBL28050574 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009111830-A1 CONJUGATED UNSATURATED COMPOUNDS COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2009-09-17 WO disclosed
WO-2009111830-A1 CONJUGATED UNSATURATED COMPOUNDS COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2009-09-17 WO disclosed