Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRIM24 | O15164 | 11/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | PKM | P14618 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | USP2 | O75604 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | NOTUM | Q6P988 | 4/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14590668 | 0.84 | TRIM24 (0.65) | TRIM24HPGDPKMSMN1; SMN2NOTUM | |
| SCHEMBL13690229 | 0.82 | PKM (0.44) | TRIM24HPGDPKMSMN1; SMN2USP2 | |
| SCHEMBL13002857 | 0.78 | NOTUM (0.65) | TRIM24HPGDPKMSMN1; SMN2LMNA | |
| SCHEMBL14148139 | 0.78 | NOTUM (0.60) | TRIM24HPGDPKMSMN1; SMN2LMNA | |
| SCHEMBL11682254 | 0.77 | SMN1; SMN2 (0.70) | TRIM24HPGDPKMSMN1; SMN2LMNA | |
| SCHEMBL3767593 | 0.76 | SMN1; SMN2 (0.72) | TRIM24HPGDPKMSMN1; SMN2LMNA | |
| SCHEMBL14590660 | 0.75 | TDP1 (0.59) | TRIM24HPGDPKMSMN1; SMN2LMNA | |
| SCHEMBL2581073 | 0.74 | PKM (1.00) | TRIM24PKMSMN1; SMN2USP2LMNA | |
| SCHEMBL4808175 | 0.74 | NOTUM (0.67) | TRIM24PKMSMN1; SMN2LMNANOTUM | |
| SCHEMBL31681375 | 0.74 | TRIM24 (0.70) | TRIM24HPGDPKMSMN1; SMN2USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009109999-A1 | NOVEL PROTEIN TYROSINE PHOSPHATASE - IB INHIBITORS | LUPIN LIMITED (IN) | 2009-09-11 | — | — | WO | disclosed |