Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.51 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.49 |
| ▸ | MCHR2 | Q969V1 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CCR5 | P51681 | 2/20 | 0.45 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.45 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.45 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.45 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.45 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4232732 | 0.91 | MCHR1 (0.44) | LTA4HMCHR1MAPTHSD17B10ALDH1A1 | |
| SCHEMBL4238693 | 0.90 | CHRM4 (0.47) | LTA4HMCHR1MCHR2MAPTHSD17B10 | |
| SCHEMBL4238698 | 0.89 | CCR5 (0.47) | LTA4HMCHR1MCHR2MAPTHSD17B10 | |
| SCHEMBL4234092 | 0.88 | SMN1; SMN2 (0.42) | MCHR1MAPTHSD17B10ALDH1A1LMNA | |
| SCHEMBL4233484 | 0.88 | CACNA1B (0.52) | MAPTHSD17B10ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL4233778 | 0.85 | MEN1 (0.42) | MAPTALDH1A1LMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL4236614 | 0.85 | MAPT (0.52) | MCHR1MCHR2MAPTHSD17B10ALDH1A1 | |
| SCHEMBL4229322 | 0.82 | MCHR1 (0.46) | LTA4HMCHR1MCHR2MAPTHSD17B10 | |
| SCHEMBL4234367 | 0.81 | SSTR5 (0.42) | MCHR1MCHR2MAPTHSD17B10ALDH1A1 | |
| SCHEMBL4238123 | 0.81 | MAPT (0.45) | LTA4HMCHR1MCHR2MAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090233910-A1 | Npy antagonists, preparation and uses | CEREP (FR) | 2009-09-17 | — | — | US | claimed |
| US-20090233910-A1 | Npy antagonists, preparation and uses | CEREP (FR) | 2009-09-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090233910-A1 | Npy antagonists, preparation and uses | NPY1R, NPY5R, NPY2R | LTA4H 1731/4885MCHR1 47/4885MCHR2 30/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.