SCHEMBL4240437

SCHEMBL4240437

CCCCC(CCCC)n1ccnc1

nearest known ligand 0.54

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CYP17A1 P05093 8/20 0.51
TBXAS1 P24557 1/20 0.44
CYP19A1 P11511 8/20 0.40
CYP1A2 P05177 1/20 0.37
CYP3A4 P08684 1/20 0.37
CYP2D6 P10635 1/20 0.37
CYP2C9 P11712 1/20 0.37
CYP2C19 P33261 1/20 0.37
PIK3R1 P27986 1/20 0.36
AKT1 P31749 1/20 0.36
AKT2 P31751 1/20 0.36
PIK3CA P42336 1/20 0.36
AKT3 Q9Y243 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27764400 0.96 CYP17A1 (0.49) CYP17A1TBXAS1CYP19A1CYP1A2CYP3A4
SCHEMBL27937683 0.94 TBXAS1 (0.49) CYP17A1TBXAS1CYP19A1CYP3A4CYP2D6
Bromide SCHEMBL28003391 0.94 CYP17A1 (0.48) CYP17A1TBXAS1CYP19A1CYP1A2CYP3A4
SCHEMBL20473728 0.94 TBXAS1 (0.49) CYP17A1TBXAS1CYP19A1CYP3A4CYP2D6
SCHEMBL28333780 0.94 TBXAS1 (0.49) CYP17A1TBXAS1CYP19A1CYP3A4CYP2D6
SCHEMBL28435580 0.94 TBXAS1 (0.49) CYP17A1TBXAS1CYP19A1CYP3A4CYP2D6
SCHEMBL15164843 0.94 TBXAS1 (0.49) CYP17A1TBXAS1CYP19A1CYP3A4CYP2D6
Bromide SCHEMBL28013295 0.93 TBXAS1 (0.47) CYP17A1TBXAS1CYP19A1CYP3A4CYP2D6
SCHEMBL19611321 0.92 TBXAS1 (0.50) CYP17A1TBXAS1CYP19A1CYP3A4CYP2D6
SCHEMBL28417238 0.92 TBXAS1 (0.50) CYP17A1TBXAS1CYP19A1CYP3A4CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009024312-A2 METHOD FOR THE PRODUCTION AND STABILIZATION OF FUNCTIONAL METAL NANOPARTICLES IN IONIC LIQUIDS ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) 2009-02-26 WO disclosed