⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8130143 | 0.75 | — | — | |
| SCHEMBL2545247 | 0.70 | — | — | |
| SCHEMBL776828 | 0.67 | — | — | |
| SCHEMBL8495146 | 0.67 | — | — | |
| SCHEMBL2004227 | 0.64 | — | — | |
| SCHEMBL242323 | 0.64 | — | — | |
| SCHEMBL1004010 | 0.64 | — | — | |
| SCHEMBL8125328 | 0.64 | — | — | |
| SCHEMBL1335608 | 0.64 | — | — | |
| SCHEMBL8129796 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 100 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240165139-A1 | GALACTOPYRANOSYL-CYCLOHEXYL DERIVATIVES AS E-SELECTIN ANTAGONISTS | GLYCOMIMETICS, INC. (US) | 2024-05-23 | — | — | US | disclosed |
| US-20240150388-A1 | HETEROBIFUNCTIONAL INHIBITORS OF E-SELECTIN AND GALECTIN-3 | GLYCOMIMETICS, INC. (US) | 2024-05-09 | — | — | US | disclosed |
| CN-113490665-B | Galectin-3 inhibiting C-glycoside | 糖模拟物有限公司 | 2024-05-07 | — | — | CN | disclosed |
| US-11878026-B2 | Galactopyranosyl-cyclohexyl derivatives as e-selectin antagonists | GLYCOMIMETICS, INC. (US) | 2024-01-23 | — | — | US | disclosed |
| US-11873317-B2 | Galectin-3 inhibiting c-glycosides | GLYCOMIMETICS, INC. (US) | 2024-01-16 | — | — | US | disclosed |
| CN-117298287-A | High potency multimeric E-selectin antagonists | 糖模拟物有限公司 | 2023-12-29 | — | — | CN | disclosed |
| US-11845771-B2 | Heterobifunctional inhibitors of E-selectin and galectin-3 | GLYCOMIMETICS, INC. (US) | 2023-12-19 | — | — | US | disclosed |
| US-20230365609-A1 | HIGHLY POTENT MULTIMERIC E-SELECTIN ANTAGONISTS | GLYCOMIMETICS, INC. (US) | 2023-11-16 | — | — | US | disclosed |
| US-20230364277-A1 | E-SELECTIN TARGETING AGENTS | GLYCOMIMETICS, INC. (US) | 2023-11-16 | — | — | US | disclosed |
| CN-109890421-B | High potency multimeric E-selectin antagonists | 糖模拟物有限公司 | 2023-10-20 | — | — | CN | disclosed |
| WO-1999029677-A1 | SUBSTITUTED 2,4-DIAMINO-1,3,5-TRIAZINES | BAYER AKTIENGESELLSCHAFT (DE) | 1999-06-17 | — | — | WO | disclosed |
| EP-0922045-A1 | BICYCLIC PYRIMIDINE DERIVATIVES AND THEIR USE AS ANTI-COAGULANTS | SCHERING AKTIENGESELLSCHAFT (DE) | 1999-06-16 | — | — | EP | disclosed |
| EP-0920430-A1 | PURINE DERIVATIVES AND THEIR USE AS ANTI-COAGULANTS | SCHERING AKTIENGESELLSCHAFT (DE) | 1999-06-09 | — | — | EP | disclosed |
| WO-1999019309-A1 | SUBSTITUTED 2,4-DIAMINO-1,3,5-TRIAZINES | BAYER AKTIENGESELLSCHAFT (DE) | 1999-04-22 | — | — | WO | disclosed |
| US-5846972-A | Bicyclic pyrimidine derivatives and their use as anti-coagulants | BERLEX LABORATORIES, INC. (US) | 1998-12-08 | — | — | US | disclosed |
| US-5846970-A | Bicyclic pyrimidine derivatives and their use as anti-coagulants | BERLEX LABORATORIES, INC. (US) | 1998-12-08 | — | — | US | disclosed |
| US-5753635-A | Purine derivatives and their use as anti-coagulants | BERLEX LABORATORIES, INC. (US) | 1998-05-19 | — | — | US | disclosed |
| WO-1998007723-A1 | BICYCLIC PYRIMIDINE DERIVATIVES AND THEIR USE AS ANTI-COAGULANTS | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-02-26 | — | — | WO | disclosed |
| WO-1998007725-A1 | PURINE DERIVATIVES AND THEIR USE AS ANTI-COAGULANTS | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-02-26 | — | — | WO | disclosed |
| US-5693641-A | ENZYME INHIBITOR TREATING BLOOD DISORDER | BERLEX LABORATORIES INC. (US) | 1997-12-02 | — | — | US | disclosed |