SCHEMBL2545247

SCHEMBL2545247

F[C](F)CBr

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4240464 0.70
SCHEMBL1004010 0.70
SCHEMBL11584249 0.70
SCHEMBL1335608 0.70
SCHEMBL153341 0.67
SCHEMBL9856399 0.62
SCHEMBL514405 0.60
SCHEMBL13719617 0.59
SCHEMBL391556 0.59
SCHEMBL4078581 0.59

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019215076-A1 PROCESS FOR PREPARING NITROGEN-CONTAINING HETEROCYCLES BAYER AKTIENGESELLSCHAFT (DE) 2019-11-14 WO claimed
WO-2024071439-A1 FUSED RING COMPOUND AND PHARMACEUTICAL CONTAINING SAME 科研製薬株式会社 2024-04-04 WO disclosed
CN-108290838-B Biaryl derivatives and drugs containing the same 科研制药株式会社 2021-12-31 CN disclosed
US-10647675-B2 Biaryl derivative and medicine containing same KAKEN PHARMACEUTICAL CO., LTD. (JP) 2020-05-12 US disclosed
EP-3319943-B1 NITROGEN-CONTAINING HETEROCYCLES AS PESTICIDES BAYER CROPSCIENCE AG (DE) 2019-06-26 EP disclosed
US-20190055199-A1 BIARYL DERIVATIVE AND MEDICINE CONTAINING SAME KAKEN PHARMACEUTICAL CO., LTD. (JP) 2019-02-21 US disclosed
EP-3351533-A1 BIARYL DERIVATIVE AND MEDICINE CONTAINING SAME Kaken Pharmaceutical Co., Ltd. (JP) 2018-07-25 EP disclosed
US-8809344-B2 Compounds, compositions, and methods for control of hepatitis C viral infections APATH, LLC (US) 2014-08-19 US disclosed
US-20110262397-A1 COMPOUNDS, COMPOSITIONS, AND METHODS FOR CONTROL OF HEPATITIS C VIRAL INFECTIONS APATH, LLC (US) 2011-10-27 US disclosed
WO-2010096115-A1 COMPOUNDS, COMPOSITIONS AND METHODS FOR CONTROL OF HEPATITIS C VIRAL INFECTIONS APATH, LLC (US) 2010-08-26 WO disclosed
WO-1992003429-A1 RENIN INHIBITORS ABBOTT LABORATORIES (US) 1992-03-05 WO disclosed
US-4087432-A HERBICIDES ELI LILLY AND COMPANY (US) 1978-05-02 US disclosed
US-4082534-A HERBICIDES ELI LILLY AND COMPANY (US) 1978-04-04 US disclosed
US-4042593-A HERBICIDES ELI LILLY AND COMPANY (US) 1977-08-16 US disclosed
US-4010168-A Naphthalide indicator dyes POLAROID CORPORATION (US) 1977-03-01 US disclosed
US-4000145-A HERBICIDES ELI LILLY AND COMPANY (US) 1976-12-28 US disclosed
US-3968116-A HERBICIDE ELI LILLY AND COMPANY (US) 1976-07-06 US disclosed
US-3963734-A HERBICIDES, HERBICIDE INTERMEDIATES ELI LILLY AND COMPANY (US) 1976-06-15 US disclosed
US-3961937-A Esters of 1-hydroxy-1H-imidazo-(4,5-b)-pyridines as herbicides ELI LILLY AND COMPANY (US) 1976-06-08 US disclosed
US-3932428-A HERBICIDES ELI LILLY AND COMPANY (US) 1976-01-13 US disclosed