SCHEMBL4241016

SCHEMBL4241016

CCCCCCCCCCCCCCC1NCCO1

nearest known ligand 0.48

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.48
ALDH1A1 P00352 2/20 0.47
GBA1 P04062 4/20 0.37
SPHK1 Q9NYA1 6/20 0.36
SPHK2 Q9NRA0 3/20 0.36
GUSB P08236 1/20 0.36
CYP1A2 P05177 3/20 0.33
GLB1 P16278 1/20 0.33
GBA2 Q9HCG7 1/20 0.33
S1PR1 P21453 1/20 0.33
S1PR3 Q99500 1/20 0.33
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3384746 1.00 EPHX1 (0.48) EPHX1ALDH1A1GBA1SPHK1SPHK2
SCHEMBL27595229 1.00 EPHX1 (0.48) EPHX1ALDH1A1GBA1SPHK1SPHK2
SCHEMBL10956633 1.00 EPHX1 (0.48) EPHX1ALDH1A1GBA1SPHK1SPHK2
SCHEMBL9662231 1.00 EPHX1 (0.48) EPHX1ALDH1A1GBA1SPHK1SPHK2
SCHEMBL1075621 0.98 EPHX1 (0.45) EPHX1ALDH1A1GBA1SPHK1SPHK2
SCHEMBL3123371 0.92
SCHEMBL6908298 0.89 ARG1 (0.33) EPHX1ALDH1A1
SCHEMBL6899828 0.89 ARG1 (0.33) EPHX1ALDH1A1
SCHEMBL9864715 0.89 ARG1 (0.33) EPHX1ALDH1A1
Acetamide SCHEMBL8209952 0.88 EPHX1 (0.40) EPHX1ALDH1A1GBA1SPHK1SPHK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009129097-A1 NITRATED HYDROCARBONS, DERIVATIVES, AND PROCESSES FOR THEIR MANUFACTURE ANGUS CHEMICAL COMPANY (US) 2009-10-22 WO disclosed