SCHEMBL4241472

SCHEMBL4241472

Oc1ccc(CC(c2ccc(O)cc2)C(c2ccc(O)cc2)c2ccc(O)cc2)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 15/20 0.55
ESR2 Q92731 14/20 0.55
CYP1A2 P05177 2/20 0.50
CYP3A4 P08684 2/20 0.50
CYP2C9 P11712 2/20 0.50
CYP2C19 P33261 2/20 0.50
SLC6A2 P23975 2/20 0.50
MEN1 O00255 1/20 0.50
ALDH1A1 P00352 1/20 0.50
KMT2A Q03164 1/20 0.50
LMNA P02545 1/20 0.50
PGR P06401 1/20 0.50
CHRM2 P08172 1/20 0.50
ADORA3 P0DMS8 1/20 0.50
AR P10275 1/20 0.50
CYP2D6 P10635 1/20 0.50
MAPT P10636 1/20 0.50
CHRM1 P11229 1/20 0.50
ALOX15 P16050 1/20 0.50
DRD1 P21728 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10774365 0.92 ESR1 (0.48) ESR1ESR2CYP1A2CYP3A4CYP2C9
SCHEMBL30453326 0.89 ESR1 (0.61) ESR1ESR2CYP1A2CYP3A4CYP2C9
SCHEMBL285683 0.81 ESR1 (0.64) ESR1ESR2CYP1A2CYP3A4CYP2C9
SCHEMBL11509582 0.77 ESR1 (0.53) ESR1ESR2CYP1A2CYP3A4CYP2C9
SCHEMBL24186779 0.76 ESR1 (0.59) ESR1ESR2CYP1A2CYP3A4CYP2C9
SCHEMBL21959544 0.75 ESR1 (0.61) ESR1ESR2CYP1A2CYP3A4CYP2C9
SCHEMBL18382530 0.75 ESR1 (0.56) ESR1ESR2CYP1A2CYP3A4CYP2C9
SCHEMBL231792 0.75 ESR1 (0.61) ESR1ESR2CYP1A2CYP3A4CYP2C9
SCHEMBL6744903 0.75 ESR1 (0.76) ESR1ESR2CYP1A2CYP3A4CYP2C9
SCHEMBL5818107 0.75 ESR1 (0.61) ESR1ESR2CYP1A2CYP3A4CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4474999-A Phenol compounds, process and polymers GENERAL ELECTRIC COMPANY (US) 1984-10-02 US claimed
US-4415724-A Branched aromatic polycarbonate from tetraphenol GENERAL ELECTRIC COMPANY (US) 1983-11-15 US claimed
US-7556902-B2 Aromatic polyester resin, and electrophotographic photoconductor and image forming apparatus using thereof RICOH COMPANY, LTD. (JP) 2009-07-07 US disclosed
US-7348113-B2 Electrophotographic photoconductor comprising a polycarbonate resin having a dihydroxy diphenyl ether unit RICOH COMPANY, LTD. (JP) 2008-03-25 US disclosed
US-7071285-B2 Aromatic polycarbonate resin, electrophotographic photoconductor, process cartridge, and electrophotographic image forming method and apparatus RICOH COMPANY, LTD. (JP) 2006-07-04 US disclosed
US-20060046169-A1 Aromatic polyester resin, and electrophotographic photoconductor and image forming apparatus using thereof RICOH COMPANY, LTD. (JP) 2006-03-02 US disclosed
US-6919419-B2 AROMATIC BLOCK POLYCARBONATE RESIN, DIPHENOL COMPOUND FOR PREPARATION OF THE POLYCARBONATE RESIN, ELECTRO-PHOTOGRAPHIC PHOTOCONDUCTOR, ELECTRO-PHOTOGRAPHIC IMAGE FORMING APPARATUS AND PROCESS, AND PROCESS CARTRIDGE RICOH COMPANY LTD. (JP) 2005-07-19 US disclosed
US-20050106483-A1 Aromatic polycarbonate resin, electrophotographic photoconductor, dihydroxy diphenyl ether compound, and process of manufacturing dihydroxy diphenyl ether compound RICOH COMPANY, LTD. (JP) 2005-05-19 US disclosed
US-20050003287-A1 Aromatic polycarbonate resin, electrophotographic photoconductor, process cartridge, and electrophotographic image forming method and apparatus RICOH COMPANY, LTD. (JP) 2005-01-06 US disclosed
US-6790571-B2 FORMED FROM N-(4-(2,2-BIS(4-HYDROXYPHENYL)VINYL)PHENYL)-N,N BIS(4-TOLYL)AMINE; IMPROVED DURABILITY; FOR USE IN ORGANIC ELECTROLUMINESCENT DEVICE RICOH COMPANY, LTD. (JP) 2004-09-14 US disclosed
US-20040002574-A1 Aromatic block polycarbonate resin, diphenol compound for preparation of the polycarbonate resin, electro-photographic photoconductor, electro-photographic image forming apparatus and process, and process cartridge RICOH COMPANY, LTD. (JP) 2004-01-01 US disclosed
US-6045959-A CHARGE TRANSPORTING POLYMER RICOH COMPANY, LTD. (JP) 2000-04-04 US disclosed
US-6018014-A PRESCRIBED DIOL MONOMER HAS STRUCTURE HYDROXY-(ARYLENE)-(2-(AMINOARYL OR HETEROCYCLE)VINYL)-(ARYLENE)-HYDROXYL;USEFUL FOR A CHARGE-TRANSPORT POLYMER MATERIAL FOR AN ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEDIUM RICOH COMPANY, LTD. (JP) 2000-01-25 US disclosed
US-5976746-A ELECTROCONDUCTIVE SUPPORT; PHOTOCONDUCTIVE LAYER RICOH COMPANY, LTD. (JP) 1999-11-02 US disclosed
US-5840454-A Aromatic polycarbonate and electrophotographic photosensitive medium using same RICOH COMPANY, LTD. (JP) 1998-11-24 US disclosed
EP-0600447-B1 Aromatic polycarbonate and production method thereof MITSUI CHEMICALS INC (JP) 1998-10-07 EP disclosed
US-5426170-A Interfacial polymerization of aromatic dihydroxy compound, carbonate precursor, alkali metal or alkaline metal base, water and solvent, endcapping MITSUI TOATSU CHEMICALS, INC. (JP) 1995-06-20 US disclosed
EP-0600447-A2 Aromatic polycarbonate and production method thereof MITSUI TOATSU CHEMICALS, Inc. (JP) 1994-06-08 EP disclosed
US-4474999-A Phenol compounds, process and polymers GENERAL ELECTRIC COMPANY (US) 1984-10-02 US disclosed
US-4415724-A Branched aromatic polycarbonate from tetraphenol GENERAL ELECTRIC COMPANY (US) 1983-11-15 US disclosed