SCHEMBL4241585

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4243584	0.84	TLR7 (0.46)	TLR7TLR8SMN1; SMN2LMNATP53
	SCHEMBL3968369	0.84	TLR7 (0.58)	TLR7TLR8SMN1; SMN2LMNAMAPT
	SCHEMBL3867677	0.81	BRD4 (0.43)	TLR7NMT1MEN1KMT2AMAPT
	SCHEMBL3872439	0.80	TLR7 (0.47)	TLR7NPC1RAB9AMEN1KMT2A
	SCHEMBL1486630	0.80	TLR7 (0.73)	TLR7TLR8
	SCHEMBL1486736	0.79	BRD4 (0.40)	TLR7NMT1HPGDSMN1; SMN2MEN1
	SCHEMBL19968181	0.79	TLR7 (0.44)	TLR7TLR8PDE4APDE4BPDE4C
	SCHEMBL1486436	0.79	TLR7 (0.45)	TLR7NMT1HPGDSMN1; SMN2DYRK1A
	SCHEMBL1486453	0.79	TLR7 (0.60)	TLR7TLR8
	SCHEMBL1486670	0.78	TLR7 (0.61)	TLR7TLR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.