Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR3 | P29371 | 20/20 | 0.72 |
| ▸ | KCNH2 | Q12809 | 14/20 | 0.72 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4237366 | 0.84 | TACR3 (1.00) | TACR3KCNH2CYP3A4 | |
| SCHEMBL4238876 | 0.83 | TACR3 (0.71) | TACR3KCNH2CYP3A4 | |
| SCHEMBL6853585 | 0.83 | POLB (0.48) | TACR3KCNH2CYP3A4 | |
| SCHEMBL4242120 | 0.81 | TACR3 (0.71) | TACR3KCNH2CYP3A4 | |
| SCHEMBL4232973 | 0.81 | TACR3 (0.70) | TACR3KCNH2CYP3A4 | |
| SCHEMBL4228709 | 0.80 | TACR3 (0.82) | TACR3KCNH2CYP3A4 | |
| SCHEMBL4239466 | 0.80 | TACR3 (0.86) | TACR3KCNH2CYP3A4 | |
| SCHEMBL4234262 | 0.80 | TACR3 (0.69) | TACR3KCNH2CYP3A4 | |
| SCHEMBL4235021 | 0.80 | TACR3 (0.73) | TACR3KCNH2CYP3A4 | |
| SCHEMBL4235015 | 0.80 | TACR3 (0.73) | TACR3KCNH2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090054440-A1 | Quinoline derivatives as neurokinin receptor antagonists | CARLING WILLIAM ROBERT | 2009-02-26 | — | — | US | claimed |
| US-20090054440-A1 | Quinoline derivatives as neurokinin receptor antagonists | CARLING WILLIAM ROBERT | 2009-02-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090054440-A1 | Quinoline derivatives as neurokinin receptor antagonists | TACR2, TACR3, NPY2R | TACR3 2/4885KCNH2 41/4885CYP3A4 1101/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.