Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | THRB | P10828 | 2/20 | 0.50 |
| ▸ | RECQL | P46063 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | BLM | P54132 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | APEX1 | P27695 | 1/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.50 |
| ▸ | GRM8 | O00222 | 1/20 | 0.43 |
| ▸ | GRM6 | O15303 | 1/20 | 0.43 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.43 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.43 |
| ▸ | GSR | P00390 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.43 |
| ▸ | GRM5 | P41594 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4242292 | 1.00 | KMT2A (0.50) | KMT2AMAPTMEN1THRBRECQL | |
| SCHEMBL7753481 | 0.89 | KMT2A (0.47) | KMT2AMAPTMEN1THRBRECQL | |
| SCHEMBL7902680 | 0.88 | MAPT (0.46) | KMT2AMAPTMEN1THRBRECQL | |
| SCHEMBL5321634 | 0.86 | GRM8 (0.42) | KMT2AMAPTMEN1THRBRECQL | |
| SCHEMBL7902684 | 0.80 | KMT2A (0.49) | KMT2AMAPTMEN1THRBRECQL | |
| SCHEMBL10613892 | 0.78 | KMT2A (0.50) | KMT2AMAPTMEN1THRBRECQL | |
| SCHEMBL5321642 | 0.78 | KMT2A (0.42) | KMT2AMAPTMEN1THRBRECQL | |
| SCHEMBL28401789 | 0.77 | DHFR (0.39) | KMT2AMAPTMEN1THRBRECQL | |
| SCHEMBL10797389 | 0.76 | MEN1 (0.47) | KMT2AMAPTMEN1THRBRECQL | |
| SCHEMBL1261533 | 0.73 | GRM8 (0.41) | MAPTGRM8GRM6GRIN2DGRIN3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140315973-A1 | PARP-1 INHIBITORS | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2014-10-23 | — | — | US | disclosed |
| WO-2013052006-A1 | PARP-1 INHIBITORS | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (A*STAR) (SG) | 2013-04-11 | — | — | WO | disclosed |
| US-7481781-B2 | Ultrasound therapy | GENDEL LIMITED (GB) | 2009-01-27 | — | — | US | disclosed |
| EP-1506039-B1 | ABLATION DEVICE | GENDEL LTD (GB) | 2008-10-29 | — | — | EP | disclosed |
| WO-2006044716-A2 | CELL PERMEABLE NANOCONJUGATES OF SHELL-CROSSLINKED KNEDEL (SCK) AND PEPTIDE NUCLEIC ACIDS ('PNAs') WITH UNIQUELY EXPRESSED OR OVER-EXPRESSED mRNA TARGETING SEQUENCES FOR EARLY DIAGNOSIS AND THERAPY OF CANCER | WASHINGTON UNIVERSITY IN ST.LOUIS (US) | 2006-04-27 | — | — | WO | disclosed |
| EP-1196143-B1 | USE OF AN ELECTRIC FIELD FOR SENSITISING RED BLOOD CELLS TO ULTRASOUND | UUTECH LTD (GB) | 2006-03-01 | — | — | EP | disclosed |
| US-20050043726-A1 | Device II | GENDEL LIMITED (GB) | 2005-02-24 | — | — | US | disclosed |
| US-6821274-B2 | DISRUPTING DISEASED AREA WHILE MINIMIZING HARM TO NEIGHBORING HEALTHY CELLS; PRETREATMENT WITH ELECTRIC FIELD | GENDEL LTD. (IE) | 2004-11-23 | — | — | US | disclosed |
| US-6812204-B1 | ELECTROSENSITIZING RED BLOOD CELL; APPLYING SOUND WAVES | GENDEL LIMITED (GB) | 2004-11-02 | — | — | US | disclosed |
| WO-2004083391-A2 | TARGETED AND REGIONAL CELLULAR ABLATION IN ZEBRAFISH | WASHINGTON UNIVERSITY IN ST. LOUIS (US) | 2004-09-30 | — | — | WO | disclosed |
| US-20010053549-A1 | Loading method | GENDEL LIMITED (GB) | 2001-12-20 | — | — | US | disclosed |
| US-20010031499-A1 | Loading system and method for using the same | GENDEL LIMITED (GB) | 2001-10-18 | — | — | US | disclosed |
| WO-2001058432-A1 | APPARATUS FOR PROVIDING A RED BLOOD CELL CARRIER | GENDEL LIMITED (GB) | 2001-08-16 | — | — | WO | disclosed |
| US-20010008758-A1 | Delivery of an agent | UUTECH LIMITED (GB) | 2001-07-19 | — | — | US | disclosed |
| EP-1078052-A2 | NONCLONING TECHNIQUE FOR EXPRESSING A GENE OF INTEREST | CHIRON CORPORATION (US) | 2001-02-28 | — | — | EP | disclosed |
| EP-0996736-A1 | METHODS FOR GENETICALLY MODIFYING T CELLS | CHIRON CORPORATION (US) | 2000-05-03 | — | — | EP | disclosed |
| EP-0970232-A2 | NON-IMMUNOGENIC PRODRUGS AND SELECTABLE MARKERS FOR USE IN GENE THERAPY | Chiron Corporation (US) | 2000-01-12 | — | — | EP | disclosed |
| WO-1999053046-A2 | NONCLONING TECHNIQUE FOR EXPRESSING A GENE OF INTEREST | CHIRON CORPORATION (US) | 1999-10-21 | — | — | WO | disclosed |
| WO-1999007870-A1 | METHODS FOR GENETICALLY MODIFYING T CELLS | CHIRON CORPORATION (US) | 1999-02-18 | — | — | WO | disclosed |
| WO-1998030709-A2 | NON-IMMUNOGENIC PRODRUGS AND SELECTABLE MARKERS FOR USE IN GENE THERAPY | CHIRON CORPORATION (US) | 1998-07-16 | — | — | WO | disclosed |