Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 20/20 | 0.46 |
| ▸ | PPARA | Q07869 | 5/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3956263 | 0.85 | PPARD (0.64) | PPARDPPARAPPARG | |
| SCHEMBL3953312 | 0.80 | PPARD (0.45) | PPARDPPARAPPARG | |
| SCHEMBL3957943 | 0.72 | AKR1C3 (0.41) | — | |
| SCHEMBL13780397 | 0.72 | AKR1C3 (0.41) | — | |
| SCHEMBL5215348 | 0.70 | PPARD (0.66) | PPARDPPARAPPARG | |
| SCHEMBL14432938 | 0.70 | PPARD (0.66) | PPARDPPARAPPARG | |
| SCHEMBL5215360 | 0.70 | PPARD (0.66) | PPARDPPARAPPARG | |
| SCHEMBL13780404 | 0.69 | MAPT (0.45) | PPARDPPARAPPARG | |
| SCHEMBL3954260 | 0.68 | PDE2A (0.40) | — | |
| SCHEMBL5860831 | 0.68 | PPARD (0.72) | PPARDPPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7504433-B2 | Thiophene derivative PPAR modulators | ELI LILLY AND COMPANY (US) | 2009-03-17 | — | — | US | claimed |