SCHEMBL4242628

SCHEMBL4242628

Cc1c(C(=S)N(O)C2CCCCC2)nc(-c2ccc(Cl)cc2Cl)n1-c1ccc(OS(=O)(=O)CCC(F)(F)F)cc1

nearest known ligand 0.69

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 20/20 0.69

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4246406 0.91 CNR1 (0.69) CNR1
SCHEMBL4247662 0.86 CNR1 (0.54) CNR1
SCHEMBL4917463 0.86 CNR1 (0.61) CNR1
SCHEMBL4638248 0.84 CNR1 (0.59) CNR1
SCHEMBL4902724 0.83 CNR1 (0.70) CNR1
SCHEMBL4896171 0.83 CNR1 (0.75) CNR1
SCHEMBL4242621 0.83 CNR1 (0.87) CNR1
SCHEMBL4246405 0.83 CNR1 (0.87) CNR1
SCHEMBL4616127 0.81 CNR1 (0.75) CNR1
SCHEMBL4614813 0.81 CNR1 (1.00) CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090156616-A1 THERAPEUTIC AGENTS ASTRAZENECA AB (SE) 2009-06-18 US claimed
US-20090156616-A1 THERAPEUTIC AGENTS ASTRAZENECA AB (SE) 2009-06-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090156616-A1 THERAPEUTIC AGENTS NLN, BDNF, GAP43 CNR1 173/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.