Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 20/20 | 0.56 |
| ▸ | ITGAV | P06756 | 20/20 | 0.56 |
| ▸ | ITGB5 | P18084 | 3/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2495277 | 0.95 | ITGB3 (0.62) | ITGB3ITGAVITGB5 | |
| SCHEMBL4247556 | 0.95 | ITGB3 (0.60) | ITGB3ITGAVITGB5 | |
| SCHEMBL861506 | 0.91 | ITGB3 (0.51) | ITGB3ITGAVITGB5 | |
| SCHEMBL2490046 | 0.90 | ITGB3 (0.63) | ITGB3ITGAVITGB5 | |
| SCHEMBL861676 | 0.87 | ITGB3 (0.56) | ITGB3ITGAVITGB5 | |
| SCHEMBL861269 | 0.87 | ITGB3 (0.57) | ITGB3ITGAVITGB5 | |
| SCHEMBL861296 | 0.86 | ITGB3 (0.58) | ITGB3ITGAVITGB5 | |
| SCHEMBL860404 | 0.85 | ITGB3 (0.57) | ITGB3ITGAVITGB5 | |
| SCHEMBL852378 | 0.84 | ITGB3 (0.75) | ITGB3ITGAVITGB5 | |
| SCHEMBL862008 | 0.84 | ITGB3 (0.57) | ITGB3ITGAVITGB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1425010-A4 | SUBSTITUTED INDOLES AND THEIR USE AS INTEGRIN ANTAGONISTS | ORTHO MCNEIL PHARM INC (US) | 2009-07-29 | — | — | EP | disclosed |
| EP-1425010-A1 | SUBSTITUTED INDOLES AND THEIR USE AS INTEGRIN ANTAGONISTS | Ortho-McNeil Pharmaceutical, Inc. (US) | 2004-06-09 | — | — | EP | disclosed |
| WO-2002060438-A1 | SUBSTITUTED INDOLES AND THEIR USE AS INTEGRIN ANTAGONISTS | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 2002-08-08 | — | — | WO | disclosed |