SCHEMBL4243407

SCHEMBL4243407

CCN(CC)c1ccc(C=Cc2ccccc2)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.61
RELA Q04206 2/20 0.61
ALDH3A1 P30838 1/20 0.61
ALDH1A3 P47895 1/20 0.61
MEN1 O00255 4/20 0.56
KMT2A Q03164 4/20 0.56
MAPT P10636 3/20 0.56
BCHE P06276 3/20 0.56
ACHE P22303 3/20 0.56
NPC1 O15118 2/20 0.56
CYP3A4 P08684 2/20 0.56
CYP1A2 P05177 1/20 0.56
CYP2D6 P10635 1/20 0.56
CYP2C19 P33261 1/20 0.56
SMN1; SMN2 Q16637 1/20 0.56
NPSR1 Q6W5P4 1/20 0.56
MAPK1 P28482 2/20 0.56
TDP1 Q9NUW8 2/20 0.56
L3MBTL1 Q9Y468 2/20 0.56
USP2 O75604 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21594497 1.00 ALDH1A1 (0.61) ALDH1A1RELAALDH3A1ALDH1A3MEN1
SCHEMBL9192952 1.00 ALDH1A1 (0.61) ALDH1A1RELAALDH3A1ALDH1A3MEN1
SCHEMBL2622612 0.92 ALDH1A1 (0.57) ALDH1A1RELAALDH3A1ALDH1A3MEN1
SCHEMBL14602215 0.92 ALDH1A1 (0.57) ALDH1A1RELAALDH3A1ALDH1A3MEN1
SCHEMBL2622641 0.92 ALDH1A1 (0.57) ALDH1A1RELAALDH3A1ALDH1A3MEN1
SCHEMBL8171054 0.91 ALDH1A1 (0.71) ALDH1A1RELAALDH3A1ALDH1A3MEN1
SCHEMBL2298602 0.91 ALDH1A1 (0.71) ALDH1A1RELAALDH3A1ALDH1A3MEN1
SCHEMBL2298605 0.91 ALDH1A1 (0.71) ALDH1A1RELAALDH3A1ALDH1A3MEN1
SCHEMBL8171052 0.91 ALDH1A1 (0.71) ALDH1A1RELAALDH3A1ALDH1A3MEN1
SCHEMBL9443248 0.90 ALDH1A1 (0.55) ALDH1A1RELAALDH3A1ALDH1A3MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103242167-A Amine compound, electrophotographic photoconductor, image forming method, image forming apparatus, and process cartridge RICOH CO LTD 2013-08-14 CN disclosed
US-8380109-B2 Image forming apparatus and process cartridge RICOH COMPANY, LTD. (JP) 2013-02-19 US disclosed
US-20100267078-A1 Selective Detection of Proteins that Contain Two or More Alpha-Helical Transmembrane Domains Life Technologies Corporation (US) 2010-10-21 US disclosed
US-20090180804-A1 Image forming apparatus and process cartridge RICOH COMPANY, LTD. 2009-07-16 US disclosed
CN-101386621-A Naphthalenetetracarboxylic acid diimide derivative and electrophotographic photoconductor having the same RICOH KK (JP) 2009-03-18 CN disclosed
CN-1169025-C Electronic photographic photoreceptor 株式会社理光 2004-09-29 CN disclosed
CN-1196506-A Electronic photographic photoreceptor RICOH KK (JP) 1998-10-21 CN disclosed
EP-0277039-B1 Electrophotograhic plate by use of metal naphthalocyanine derivative HITACHI CHEMICAL CO LTD (JP) 1995-10-04 EP disclosed
EP-0594697-A1 NONLINEAR OPTICAL MATERIALS CONTAINING POLAR DISULFONE-FUNCTIONALIZED MOLECULES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1994-05-04 EP disclosed
EP-0248590-B1 1,1,4,4-TETRAPHENYL-1,3- BUTADIENE DERIVATIVES AND ELECTROPHOTOGRAPHIC LIGHTSENSITIVE MATERIAL CONTAINING THEM Takasago Perfumery Co., Ltd. (JP) 1991-08-21 EP disclosed
US-5021563-A For electrophotography HITACHI CHEMICAL COMPANY, LTD. (JP) 1991-06-04 US disclosed
US-4886721-A GERMANIUM OR TIN DERIVATIVE HITACHI CHEMICAL COMPANY, LTD. (JP) 1989-12-12 US disclosed
US-4830943-A Bisazo compounds and electrophotographic photoconductors comprising the bisazo compounds RICOH COMPANY, LTD. (JP) 1989-05-16 US disclosed
EP-0277039-A2 Electrophotograhic plate by use of metal naphthalocyanine derivative Hitachi Chemical Co., Ltd. (JP) 1988-08-03 EP disclosed
EP-0026088-B1 PHOTORESIST COMPOSITIONS JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1983-11-23 EP disclosed
US-4349619-A CONTAINING ANTIHALATION AGENTS JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1982-09-14 US disclosed