Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VNN1 | O95497 | 2/20 | 0.44 |
| ▸ | NAMPT | P43490 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | SETDB1 | Q15047 | 1/20 | 0.42 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.37 |
| ▸ | MET | P08581 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1706646 | 0.76 | L3MBTL1 (0.65) | L3MBTL1KMT2AMEN1 | |
| SCHEMBL29681615 | 0.76 | L3MBTL1 (0.65) | L3MBTL1KMT2AMEN1 | |
| SCHEMBL31310698 | 0.76 | CTDSP1 (0.38) | VNN1NAMPTCYP2C9CTDSP1CYP1A2 | |
| SCHEMBL1272007 | 0.76 | CTDSP1 (0.42) | VNN1NAMPTCYP2C9CTDSP1CYP1A2 | |
| SCHEMBL9290553 | 0.75 | — | — | |
| SCHEMBL9402 | 0.72 | CYP2C9 (0.48) | VNN1NAMPTCYP2C9CTDSP1CYP1A2 | |
| SCHEMBL12079383 | 0.72 | CTDSP1 (0.42) | VNN1NAMPTCYP2C9CTDSP1CYP1A2 | |
| SCHEMBL8230937 | 0.71 | NPSR1 (0.62) | VNN1NAMPTCYP2C9SETDB1CTDSP1 | |
| SCHEMBL19764921 | 0.71 | CTDSP1 (0.43) | VNN1NAMPTCYP2C9CTDSP1CYP1A2 | |
| SCHEMBL22256163 | 0.70 | CYP1A2 (0.41) | VNN1NAMPTCYP2C9CTDSP1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2049494-A2 | TYROSINE KINASE INHIBITORS | Merck & Co., Inc. (US) | 2009-04-22 | — | — | EP | claimed |
| WO-2008008310-A2 | TYROSINE KINASE INHIBITORS | MERCK & CO., INC. (US) | 2008-01-17 | — | — | WO | claimed |