SCHEMBL4243596

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4065587	0.89	TLR7 (0.57)	TLR7TLR8
	SCHEMBL4239486	0.88	TLR8 (0.41)	TLR7TLR8SUCNR1BRD4CA12
	SCHEMBL1486748	0.83	TLR7 (0.38)	TLR7TLR8
	SCHEMBL4239847	0.83	TLR7 (0.42)	TLR7TLR8BRD4
	SCHEMBL4239964	0.83	TLR7 (0.46)	TLR7TLR8BRD4CA12CA1
	SCHEMBL5617558	0.82	TLR7 (0.39)	TLR7TLR8
	SCHEMBL5618348	0.82	TLR7 (0.49)	TLR7TLR8
	SCHEMBL4240192	0.81	TLR7 (0.55)	TLR7TLR8
	SCHEMBL4247184	0.81	TLR8 (0.45)	TLR7TLR8SUCNR1BRD4CA12
	SCHEMBL2744880	0.79	TLR7 (0.46)	TLR7TLR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.