SCHEMBL424368

SCHEMBL424368

C=C(C(=O)O)C1CC1.C=CC(=O)OCCCCC

nearest known ligand 0.58

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 8/20 0.58
HPGD P15428 1/20 0.58
ALDH1A1 P00352 3/20 0.50
CYP3A4 P08684 1/20 0.50
HCAR2 Q8TDS4 3/20 0.46
ATM Q13315 1/20 0.41
NAAA Q02083 1/20 0.40
TP53 P04637 2/20 0.39
HIF1A Q16665 2/20 0.39
HSD17B10 Q99714 1/20 0.39
THRB P10828 2/20 0.37
PRKCA P17252 2/20 0.36
EPHX1 P07099 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17181058 0.99 TSHR (0.57) TSHRHPGDALDH1A1CYP3A4HCAR2
SCHEMBL48291 0.96 TSHR (0.65) TSHRHPGDALDH1A1CYP3A4HCAR2
SCHEMBL421692 0.90 TSHR (0.50) TSHRHPGDALDH1A1CYP3A4HCAR2
Acrylic Acid Ethyl Ester SCHEMBL48460 0.83 TSHR (0.41) TSHRHPGDALDH1A1CYP3A4HCAR2
SCHEMBL422866 0.83 TSHR (0.50) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL27626044 0.82 TSHR (0.71) TSHRHPGDALDH1A1CYP3A4HCAR2
Methacrylic Acid SCHEMBL312443 0.82 TSHR (0.70) TSHRHPGDALDH1A1CYP3A4HCAR2
SCHEMBL33111 0.81 TSHR (0.88) TSHRHPGDALDH1A1CYP3A4HCAR2
Methacrylic Acid SCHEMBL25389673 0.80 TSHR (0.68) TSHRHPGDALDH1A1CYP3A4HCAR2
Methacrylic Acid SCHEMBL3798546 0.80 TSHR (0.68) TSHRHPGDALDH1A1CYP3A4HCAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8940834-B2 Partially aromatic polyamide moulding compositions and their uses EMS-PATENT AG (CH) 2015-01-27 US claimed
EP-2410020-B1 Partially aromatic polyamide moulding compositions and their applications EMS PATENT AG (CH) 2013-01-30 EP claimed
US-20120022194-A1 PARTIALLY AROMATIC POLYAMIDE MOULDING COMPOSITIONS AND THEIR USES EMS-PATENT AG (CH) 2012-01-26 US claimed
US-8940834-B2 Partially aromatic polyamide moulding compositions and their uses EMS-PATENT AG (CH) 2015-01-27 US disclosed
US-20120022194-A1 PARTIALLY AROMATIC POLYAMIDE MOULDING COMPOSITIONS AND THEIR USES EMS-PATENT AG (CH) 2012-01-26 US disclosed
EP-0356978-B1 Toughened nylons characterized by low mold deposit DU PONT (US) 1999-05-06 EP disclosed
US-4977216-A BLENDS OF POLYAMIDES AND ETHYLENE IONOMER E. I. DU PONT DE NEMOURS AND COMPANY (US) 1990-12-11 US disclosed
EP-0356978-A2 Toughened nylons characterized by low mold deposit E.I. DU PONT DE NEMOURS AND COMPANY (US) 1990-03-07 EP disclosed