SCHEMBL422866

SCHEMBL422866

C=C(C(=O)O)C1CC1.C=CC(=O)OCCOCC

nearest known ligand 0.50

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TSHR P16473 9/20 0.50
ALDH1A1 P00352 5/20 0.50
TP53 P04637 2/20 0.50
HIF1A Q16665 2/20 0.50
HSD17B10 Q99714 1/20 0.50
THRB P10828 3/20 0.47
HPGD P15428 1/20 0.42
CYP3A4 P08684 1/20 0.39
EPHX2 P34913 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL421692 0.87 TSHR (0.50) TSHRALDH1A1TP53HIF1AHSD17B10
Acrylic Acid Ethyl Ester SCHEMBL48460 0.86 TSHR (0.41) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL48291 0.84 TSHR (0.65) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL424368 0.83 TSHR (0.58) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL29015789 0.82 TSHR (0.56) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL17181058 0.82 TSHR (0.57) TSHRALDH1A1TP53HIF1AHSD17B10
Methacrylic Acid SCHEMBL6060812 0.82 TSHR (0.60) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL26250 0.81 TSHR (0.75) TSHRALDH1A1TP53HIF1AHSD17B10
Methacrylic Acid SCHEMBL6060167 0.80 TSHR (0.63) TSHRALDH1A1TP53HIF1AHSD17B10
Acrylic Acid SCHEMBL9736587 0.80 TSHR (0.67) TSHRALDH1A1TP53HIF1AHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8940834-B2 Partially aromatic polyamide moulding compositions and their uses EMS-PATENT AG (CH) 2015-01-27 US claimed
EP-2410020-B1 Partially aromatic polyamide moulding compositions and their applications EMS PATENT AG (CH) 2013-01-30 EP claimed
US-20120022194-A1 PARTIALLY AROMATIC POLYAMIDE MOULDING COMPOSITIONS AND THEIR USES EMS-PATENT AG (CH) 2012-01-26 US claimed
US-8940834-B2 Partially aromatic polyamide moulding compositions and their uses EMS-PATENT AG (CH) 2015-01-27 US disclosed
US-20120022194-A1 PARTIALLY AROMATIC POLYAMIDE MOULDING COMPOSITIONS AND THEIR USES EMS-PATENT AG (CH) 2012-01-26 US disclosed
EP-0356978-B1 Toughened nylons characterized by low mold deposit DU PONT (US) 1999-05-06 EP disclosed
US-4977216-A BLENDS OF POLYAMIDES AND ETHYLENE IONOMER E. I. DU PONT DE NEMOURS AND COMPANY (US) 1990-12-11 US disclosed
EP-0356978-A2 Toughened nylons characterized by low mold deposit E.I. DU PONT DE NEMOURS AND COMPANY (US) 1990-03-07 EP disclosed