SCHEMBL4243748

SCHEMBL4243748

C[CH]OC(F)(F)C(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9522962 0.83
SCHEMBL4873405 0.71
SCHEMBL5917987 0.71
SCHEMBL7519288 0.71
SCHEMBL1498090 0.70
SCHEMBL22558840 0.69
SCHEMBL22558842 0.69
SCHEMBL9846 0.67
SCHEMBL10866796 0.67
SCHEMBL4866794 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180020662-A1 Substituted 1-cycloalkyl-2-oxotetrahydroquinolin-6-ylsulfonamides or salts thereof and use thereof to increase stress tolerance in plants BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2018-01-25 US claimed
US-20180199575-A1 SUBSTITUTED OXOTETRAHYDROQUINOLINYLPHOSPHINIC ACID AND PHOSPHINIC ACID AMIDES OR SALTS THEREOF AND USE THEREOF TO INCREASE STRESS TOLERANCE IN PLANTS BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2018-07-19 US disclosed
EP-3322296-A1 SUBSTITUTED OXO-TETRAHYDROQUINOLINYL-PHOSPHINIC ACID AND PHOSPHINIC ACID AMIDES OR SALTS THEREOF AND USE THEREOF TO INCREASE STRESS TOLERANCE IN PLANTS Bayer CropScience Aktiengesellschaft (DE) 2018-05-23 EP disclosed
US-20180020662-A1 Substituted 1-cycloalkyl-2-oxotetrahydroquinolin-6-ylsulfonamides or salts thereof and use thereof to increase stress tolerance in plants BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2018-01-25 US disclosed
EP-2970146-B1 ACYLAMINOCYCLOALKYL COMPOUNDS SUITABLE FOR TREATING DISORDERS THAT RESPOND TO MODULATION OF DOPAMINE D3 RECEPTOR ABBVIE DEUTSCHLAND (DE) 2017-11-01 EP disclosed
EP-2909201-B1 ACYLAMINOCYCLOALKYL COMPOUNDS SUITABLE FOR TREATING DISORDERS THAT RESPOND TO MODULATION OF DOPAMINE D3 RECEPTOR ABBVIE DEUTSCHLAND (DE) 2017-02-22 EP disclosed
US-20170027172-A1 USE OF SUBSTITUTE OXO TETRAHYDROQUINOLINE SULFONAMIDES OR SALTS THEREOF FOR RAISING STRESS TOLERANCE OF PLANTS BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2017-02-02 US disclosed
US-9388141-B2 Acylaminocycloalkyl compounds suitable for treating disorders that respond to modulation of dopamine D3 receptor ABBVIE INC. (US) 2016-07-12 US disclosed
US-9388148-B2 Acylaminocycloalkyl compounds suitable for treating disorders that respond to modulation of dopamine D3 receptor ABBVIE INC. (US) 2016-07-12 US disclosed
US-9376396-B2 Acylaminocycloalkyl compounds suitable for treating disorders that respond to modulation of dopamine D3 receptor AbbVie Deutschland GmbH & Co. KG (DE) 2016-06-28 US disclosed
EP-1697357-A2 TRICYCLIC BENZIMIDAZOLES Altana Pharma AG (DE) 2006-09-06 EP disclosed
WO-2005103057-A1 6,7-DIHYDROXY-8-PHENYL-3,6,7,8-TETRAHYDRO-CHROMENO[7, 8-D]IMIDAZOLE DERIVATIVES AND THEIR USE AS GASTRIC ACID SECRETION INHIBITORS ALTANA PHARMA AG (DE) 2005-11-03 WO disclosed
WO-2005058893-A1 TRICYCLIC BENZIMIDAZOLES ALTANA PHARMA AG (DE) 2005-06-30 WO disclosed
EP-0338424-B1 N-((6-trifluoromethylpyrimidin-2-yl)-aminocarbonyl)-2-carboalkoxy-benzenesulfonamides, process for their preparation and their use BASF AG (DE) 1993-11-24 EP disclosed
US-5143538-A Sulfonyl urea herbicides WESTPHALEN KARL OTTO (DE) 1992-09-01 US disclosed
US-5069710-A PRE-AND POSTEMERGENCE HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 1991-12-03 US disclosed
EP-0338424-A2 N-((6-trifluoromethylpyrimidin-2-yl)-aminocarbonyl)-2-carboalkoxy-benzenesulfonamides, process for their preparation and their use BASF Aktiengesellschaft (DE) 1989-10-25 EP disclosed
US-4577040-A Method for preparing diorganopolysiloxanes containing fluoroalkyl groups WACKER-CHEMIE GMBH (DE) 1986-03-18 US disclosed
US-4549004-A ANTIFOAM LUBRICANT WACKER-CHEMIE GMBH (DE) 1985-10-22 US disclosed
US-4489201-A Fluoroalkyloxylakyl containing organopolysiloxanes WACKER-CHEMIE GMBH (DE) 1984-12-18 US disclosed