SCHEMBL1498090

SCHEMBL1498090

CC[CH]OC(F)(F)C(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10866796 0.81
SCHEMBL9408163 0.81
SCHEMBL10867383 0.78 TSHR (0.31)
SCHEMBL9840480 0.76
SCHEMBL10866366 0.76 FAAH (0.33)
SCHEMBL3841853 0.73
SCHEMBL5411137 0.73
SCHEMBL4243748 0.70
SCHEMBL6366441 0.70
SCHEMBL8936653 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180020662-A1 Substituted 1-cycloalkyl-2-oxotetrahydroquinolin-6-ylsulfonamides or salts thereof and use thereof to increase stress tolerance in plants BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2018-01-25 US claimed
US-20180199575-A1 SUBSTITUTED OXOTETRAHYDROQUINOLINYLPHOSPHINIC ACID AND PHOSPHINIC ACID AMIDES OR SALTS THEREOF AND USE THEREOF TO INCREASE STRESS TOLERANCE IN PLANTS BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2018-07-19 US disclosed
EP-3322296-A1 SUBSTITUTED OXO-TETRAHYDROQUINOLINYL-PHOSPHINIC ACID AND PHOSPHINIC ACID AMIDES OR SALTS THEREOF AND USE THEREOF TO INCREASE STRESS TOLERANCE IN PLANTS Bayer CropScience Aktiengesellschaft (DE) 2018-05-23 EP disclosed
US-20180020662-A1 Substituted 1-cycloalkyl-2-oxotetrahydroquinolin-6-ylsulfonamides or salts thereof and use thereof to increase stress tolerance in plants BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2018-01-25 US disclosed
US-20170027172-A1 USE OF SUBSTITUTE OXO TETRAHYDROQUINOLINE SULFONAMIDES OR SALTS THEREOF FOR RAISING STRESS TOLERANCE OF PLANTS BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2017-02-02 US disclosed
US-8779054-B2 Aqueous crosslinkable dispersions based on organosilicon compounds WACKER CHEMIE AG (DE) 2014-07-15 US disclosed
US-20130253129-A1 AQUEOUS CROSSLINKABLE DISPERSIONS BASED ON ORGANOSILICON COMPOUNDS WACKER CHEMIE AG (DE) 2013-09-26 US disclosed
US-20110263751-A1 Highly Hydrophobic Coatings WACKER CHEMIE AG (DE) 2011-10-27 US disclosed
US-7972682-B2 Reactive silicic acid suspensions WACKER CHEMIE AG (DE) 2011-07-05 US disclosed
US-7901502-B2 Stable, aqueous dispersion of two chemically different particles types of a diameter of &gt;100mu m. where the isoelectric points differ by &gt; half a pH unit; a silicic acid and an oxide of aluminum, boron, zirconiuim, zinc, cerium and or iron; polishing; coatings; corrosion resistance for metals; recording WACKER CHEMIE AG (DE) 2011-03-08 US disclosed
US-4710558-A Process for stabilizing organopolysiloxanes WACKER CHEMIE GMBH (DE) 1987-12-01 US disclosed
US-4692474-A Method for preparing plastic foams WACKER-CHEMIE GMBH (DE) 1987-09-08 US disclosed
US-4680365-A Method for preparing acetoxysiloxanes and organo(poly)siloxanes having halogen bonded to silicon WACKER-CHEMIE GMBH (DE) 1987-07-14 US disclosed
US-4675425-A Method for preparing organosilyl carbonates WACKER CHEMIE GMBH (DE) 1987-06-23 US disclosed
US-4607115-A Method for increasing the molecular weight of diorganopolysiloxanes WACKER-CHEMIE GMBH (DE) 1986-08-19 US disclosed
US-4605567-A PHOTOPOLYMERIZATION OF ALLYL ANHYDRIDE-MODIFIED POLYSILOXANES REACTED WITH HYDROXYETHYL ACRYLATE WACKER-CHEMIE GMBH (DE) 1986-08-12 US disclosed
US-4599437-A Continuous process for varying molecular weight of organopolysiloxanes WACKER-CHEMIE GMBH (DE) 1986-07-08 US disclosed
US-4577040-A Method for preparing diorganopolysiloxanes containing fluoroalkyl groups WACKER-CHEMIE GMBH (DE) 1986-03-18 US disclosed
US-4549004-A ANTIFOAM LUBRICANT WACKER-CHEMIE GMBH (DE) 1985-10-22 US disclosed
US-4489201-A Fluoroalkyloxylakyl containing organopolysiloxanes WACKER-CHEMIE GMBH (DE) 1984-12-18 US disclosed